Hyaluronic acid hydrogel for controlled self-renewal and differentiation of human embryonic stem cells

S Gerecht, JA Burdick, LS Ferreira… - Proceedings of the …, 2007 - National Acad Sciences
… We report that a completely synthetic hydrogel matrix can support (i) long-term self-renewal
of … medium from mouse embryonic fibroblast feeder layers, and (ii) direct cell differentiation. …

Enzyme-mediated hyaluronic acid–tyramine hydrogels for the propagation of human embryonic stem cells in 3D

K Xu, K Narayanan, F Lee, KH Bae, S Gao, M Kurisawa - Acta biomaterialia, 2015 - Elsevier
… of hydrogels on the self-renewal properties of hESCs in 3D. Then, we characterized hESCs
cultured in hydrogels with … Hence, we demonstrated a reliable approach for the controlled

Hyaluronic acid hydrogels, as a biological macromolecule-based platform for stem cells delivery and their fate control: A review

Y Fang, L Shi, Z Duan, S Rohani - International journal of biological …, 2021 - Elsevier
… to their strong paracrine secretions, self-renewal potential, anti-… , stem cells contribute in
tissue repair through differentiation, … Human embryonic stem cell derived-neural stem cells were …

Glycosaminoglycan-binding hydrogels enable mechanical control of human pluripotent stem cell self-renewal

S Musah, SA Morin, PJ Wrighton, DB Zwick, S Jin… - ACS …, 2012 - ACS Publications
… of human embryonic stem cells on defined hydrogels presenting … Having identified a
hydrogel that functions in a chemically … of hydrogel mechanical properties on hES cell self-renewal. …

Cartilage repair using hyaluronan hydrogel-encapsulated human embryonic stem cell-derived chondrogenic cells

WS Toh, EH Lee, XM Guo, JKY Chan, CH Yeow… - Biomaterials, 2010 - Elsevier
… when cultured in hyaluronic acid (HA)-based hydrogel, and … native control, while only
fibrous tissue filled in the control … unlimited self-renewal capacity and ability to differentiate into …

Three-dimensional hydrogel scaffolds facilitate in vitro self-renewal of human skin-derived precursors

X Wang, S Liu, Q Zhao, N Li, H Zhang, X Zhang, X Lei… - Acta Biomaterialia, 2014 - Elsevier
… defined hyaluronic acid and denatured collagen-based hydrogelEmbryonic stem cells, for
example, showed greatly … , and the differences between hydrogel groups and control groups …

The application of hyaluronic acid hydrogels to retinal progenitor cell transplantation

Y Liu, R Wang, TI Zarembinski, N Doty… - … engineering Part A, 2013 - liebertpub.com
… and differentiation of human embryonic stem cellsProc Natl Acad Sci USA… Hyaluronic
acid hydrogel for controlled self-renewal and differentiation of human embryonic stem cells

Dynamic gelatin-based hydrogels promote the proliferation and self-renewal of embryonic stem cells in long-term 3D culture

Q Feng, X Ma, Y Deng, K Zhang, HS Ooi, B Yang… - Biomaterials, 2022 - Elsevier
self-renewal of mESCs in GelCD hydrogels, we also fabricated covalently crosslinked
methacryloyl gelatin (GelMA) hydrogels … By using the GelMA-1 hydrogels as the control group, we …

Natural and Synthetic Materials for SelfRenewal, Long‐Term Maintenance, and Differentiation of Induced Pluripotent Stem Cells

NA Dzhoyashvili, S Shen… - Advanced Healthcare …, 2015 - Wiley Online Library
… Hyaluronan (also called hyaluronic acid or HA) hydrogels … , and degradation can be well
controlled. Interestingly, MEFs, which … The hydrogel was tested for mouse embryonic stem cells (…

Methacrylated hyaluronic acid–based hydrogels maintain stemness in human dental pulp stem cells

KK Niloy, M Gulfam, KB Compton, D Li… - Regenerative …, 2020 - Springer
… : (i) control cells grown in culture wells, (ii) cells in culture wells treated with UV, (iii) …
Engineering integrin signaling for promoting embryonic stem cell self-renewal in a precisely …