Identification of a novel DRB1 allele through intergenic recombination between HLA-DRB1 and HLA-DRB3∗ 02 in a Chinese family
W Huang, X Liu, E Li, C Zhao, Q Liu, Z Liang, Y Wang… - Human Immunology, 2013 - Elsevier
… of a DRB1 and DRB3 intergenic recombination event involving … a novel intergenic recombinant
between human HLA DRB1 and DRB3 genes has generated a unique new DRB1 allele. …
between human HLA DRB1 and DRB3 genes has generated a unique new DRB1 allele. …
[HTML][HTML] Three deduced probable human-leukocyte-antigen haplotypes associated with HLA-DQB1* 03: 26 and-DRB1* 14: 141 from Taiwanese unrelated bone …
KL Yang - Tzu Chi Medical Journal, 2015 - Elsevier
… HLA-B, and HLA-DRB1 alleles commonly shared by the HLA … a recombination event, where
its entire exon 2 is identical to … identified together with the Chinese ethnicity of DRB1*14:141 …
its entire exon 2 is identical to … identified together with the Chinese ethnicity of DRB1*14:141 …
[HTML][HTML] HLA haplotype in association with the low incidence C* 07: 66 allele found by case analysis of Taiwanese and mainland Chinese individuals
KL Yang, ZZ Zheng - Tzu Chi Medical Journal, 2016 - Elsevier
… and HLA-DRB1 alleles commonly shared across our randomized unrelated donors and
family members with the C*07:66 allele. … , through four family studies, we found that DRB1*12:02, …
family members with the C*07:66 allele. … , through four family studies, we found that DRB1*12:02, …
HLA alleles and haplotypes observed in 263 US families
K Osoegawa, KC Mallempati, S Gangavarapu, A Oki… - Human immunology, 2019 - Elsevier
… identifying novel variants, confirming them using HLA allele … and HLA-DRB3/4/5 loci display
no overall deviation from HWE, … ∼HLA-DRB1∼HLA-DQB1 haplotypes from this family study …
no overall deviation from HWE, … ∼HLA-DRB1∼HLA-DQB1 haplotypes from this family study …
HLA-D and PLA2R1 risk alleles associate with recurrent primary membranous nephropathy in kidney transplant recipients
L Berchtold, E Letouzé, MP Alexander, G Canaud… - Kidney international, 2021 - Elsevier
… Seven SNPs located between HLA-DRB1 and HLA-DQA1 in … in Han Chinese. Furthermore,
strong gene-gene interaction … SNP, rs13018963, intergenic between PLA2R1 and ITGB6 that …
strong gene-gene interaction … SNP, rs13018963, intergenic between PLA2R1 and ITGB6 that …
[HTML][HTML] Deduced probable HLA haplotypes associated with HLA-C* 04: 82 found by case analysis of Taiwanese individuals
KL Yang - Tzu Chi Medical Journal, 2016 - Elsevier
… family study and the HLA-A, HLA-B, HLA-C, and HLA-DRB1 … in this study the oriental ethnicity
of C*04:82 was identified. In … to be not restricted to A*24:02 and DRB1*04:03, respectively. …
of C*04:82 was identified. In … to be not restricted to A*24:02 and DRB1*04:03, respectively. …
HLA Haplotype Validator for quality assessments of HLA typing
K Osoegawa, SJ Mack, J Udell, DA Noonan… - Human immunology, 2016 - Elsevier
… intra- and intergenic recombination and short-tract gene … haplotypes from HLA-DRB3/4/5,
HLA-DRB1 and HLA-DQB1 alleles … family confirming the transmission of a novel HLA-B allele …
HLA-DRB1 and HLA-DQB1 alleles … family confirming the transmission of a novel HLA-B allele …
Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans
KB Hanscombe, DL Morris, JA Noble… - Human molecular …, 2018 - academic.oup.com
… in AA consistent with the elevated level of recombination in this … In East Asian SLE the MHC
risk is also strong, but may be … for HLA alleles nested within the two-digit HLA-DRB1 * 15 …
risk is also strong, but may be … for HLA alleles nested within the two-digit HLA-DRB1 * 15 …
The MHC in the era of next-generation sequencing: Implications for bridging structure with function
EW Petersdorf, C O'hUigin - Human immunology, 2019 - Elsevier
… the 130 kb intergenic region between HLA-DRB1 and DQA1 and is … GWAS of Asian patients
pointed to HLA-DP variation as … at the low-expression HLA-DRB3, DRB4 and DRB5 genes …
pointed to HLA-DP variation as … at the low-expression HLA-DRB3, DRB4 and DRB5 genes …
[HTML][HTML] Deduced probable HLA-C* 07: 359-associated human leukocyte antigen haplotypes found by case analysis of Taiwanese unrelated bone marrow …
KL Yang - Tzu Chi Medical Journal, 2016 - Elsevier
… the HLA-DRB1 locus, using group-specific primer sets. The amplicons were sequenced in
both directions using … marrow donor registries when patients carry this uncommon HLA allele. …
both directions using … marrow donor registries when patients carry this uncommon HLA allele. …