… and broad usage of amitriptyline for the management of chronic neuropathic pain in South
… tailoring treatment and thereby improving amitriptyline efficacy in these patients. To test this …

… been used for treatment of chronic pain (amitriptyline, duloxetine, … applied towards improving
drug efficacy, shortening the time … efficacy and the side effect profile of oxycodone; CYP2D6 …

… and CYP2D6 genotypes and amitriptyline pharmacokinetics … in the amitriptyline analgesic
efficacy in CYP2D6 NMs by … effects in patients with diabetic peripheral neuropathy with …

… incidence of side effects and treatment effects with amitriptyline and … Thus, CYP2D6 genotypes
have been removed from … We questioned whether the increased therapeutic efficacy of C …

… the translation of genotype to phenotype for CYP2D6 is often performed … , amitriptyline and
nortriptyline also undergo CYP2D6 … , studies have demonstrated a probable reduced efficacy …

… The efficacy of drugs for neuropathic pain has been established in … The combination of
amitriptyline and fluphenazine was not … among healthy volunteers and/or on pilot studies among …

… This open-label pilot study is aimed to evaluate the efficacy … 30 patients with oxaliplatin-induced
peripheral neuropathy … in our study was consistent with its effect in the treatment of DPNP…

… 2017 has seen Pharmacogenomics publish novel, high-impact … a pilot study of the effect of
CYP2D6 genotype on amitriptyline efficacy for the treatment of diabetic peripheral neuropathy …

… of CYP2D6 genotype on the beneficial and adverse effects of … the extremes regarding drug
effectiveness and response who … high risk for side effects in amitriptyline therapy. Clin. Chem. …

… Opioid effectiveness in treating neuropathic pain is poorly … of fewer anticholinergic side
effects. Tricyclic antidepressants block … It is O-demethylated by CYP2D6 to desvenlafaxine that is …