… that rhizoxin was approximately twice as active in vitro … line with non-Pglycoprotein-mediated
resistance to vindesine, … activity of rhizoxin on non-P-glycoprotein-mediated vindesine-re…

CiNii 博士論文 - In vitro and in vivo modulation by rhizoxin of non-P-glycoprotein-mediated
vindesine resistance … In vitro and in vivo modulation by rhizoxin of non-P-glycoprotein-mediated …

… We also used the non-P-glycoprotein-mediated paclitaxel- … Paclitaxel- and vindesine-resistant
cells were not cross-resistant … These results suggest that cytokines may not modulate the …

… , rhizoxin demonstrated broad antitumor activity in vitro and in vivo including both vincristine-
and vindesine-resistant … behavior of rhizoxin, the feasibility of administering rhizoxin as a 72-…

… murine tumor cells resistant to vincristine and adriamycin … in vivo tumor growth was markedly
reduced by rhizoxin [325]. … xenograft model in vivo, as well as modulated a pancreatic tumor …

… antimitotic agents such as vindesine, paclitaxel and docetaxel out of … of non-P-glycoproteinmediated
multidrug resistance. Such … binding and modulation of the multidrug-resistant pheno- …

… Arioka H, Nishio K, Heike Y et al (1997) In vitro and in vivo modulation by rhizoxin of non-Pglycoprotein-mediated
vindesine resistance. J Cancer Res Clin Oncol 123: 195–200 23. …