… Our results suggest that a blunted insulin-mediated suppression of SM lipolysis may promote
the … mechanism involved in the progression of insulin resistance towards type 2 diabetes. …

… was reduced in obese subjects (2). Subsequent studies in other … uptake in insulin resistance
and type 2 diabetes (5). … An important action of insulin on fat cells is to restrain lipolysis, both …

… obese subjects have impaired insulin-mediated suppression … Subjects who had diabetes
were excluded from participating … a 2-h oral glucose tolerance test (all subjects had 2 h plasma …

… glucose uptake from the skeletal muscle and adipose tissue, as well as to inhibit lipolysis
in fat … failed to reveal a defect in insulin-mediated blood flow in type 2 diabetic patients[42,50]. …

… Normal glucose tolerance was found in all subjects except one … Insulinmediated glucose
turnover is assessed as the … insulin concentrations of skeletal muscle should be proportional to …

… of impaired glucose tolerance and impaired fasting glucose. … Insulin action and resistance
in obesity and type 2 diabetes. … (TAG) stores in adipose tissue (lipolysis) provide substrates for …

… insulin-mediated suppression of adipose tissue lipolysis is the … hepatic, not skeletal muscle
or adipose tissue insulin sensitivity … post-oral glucose tolerance test (OGTT) plasma glycerol …

… of the complications of obesity such as type 2 diabetes and … WAT lipolysis and glucose
metabolism in WAT, skeletal muscle, … to produce insulin could modify glucose tolerance, we then …

… of glucose tolerance preceding type 2 diabetes comes from … concentrations [47] in skeletal
muscle of type 2 diabetes … within adipose tissue, inhibit insulin- mediated lipolysis in white …

… Although obesity is the result of adipose tissue expansion, it is … in adipose tissue impairs
whole body glucose tolerance [26]. … of glycerol by lipolysis is not recaptured by adipose tissue, …