… dysfunction observed in WT mice was nearly absent in Nrf2 -/- mice. In summary, Iso
ameliorated APAP-induced hepatotoxicity by activating Nrf2 via the AMPK/Akt/GSK3β pathway. …

… observed in WT mice was nearly absent in Nrf2^-/- mice. In summary, Iso
ameliorated APAP-induced hepatotoxicity by activating Nrf2 via the AMPK/Akt/GSK3β pathway.</p>…

… In vivo, xanthohumol significantly ameliorated acetaminophen-… to activate Nrf2, Nrf2-mediated
the expression of antioxidant … APAP-induced liver injury through the AMPK/Akt/GSK3β/Nrf2 …

… is capable of ameliorating APAP-induced liver injury. The … with the antioxidant response
element located in promoters of Nrf2-… , isoorientin, and pterostilbene, were capable of relieving …

… and antioxidant activities (Anilkumar et al., 2017). And, we found that … ameliorates
APAP-induced hepatotoxicity via the activation of the Nrf2 antioxidative pathway and the involvement …

… defense via activation of the AMPK/SIRT3 signaling pathway. … of natural antioxidants in
treating APAP-induced ALI. … against APAP-induced ALI by activating the Keap1/Nrf2 pathway-…

… the APAP-induced increases in serum AST, ALT and LDH activity and ameliorated hepatocyte
… , thereby enhancing the antioxidant defense system to prevent APAP-induced oxidative …

… Likewise, NRF2 target gene products include antioxidant … partnership with the NRF2 signaling
pathway has been … an important role of NRF2 for lung cancer progression, the nano-NRF2 …

… to activate Nrf2 and consequently ameliorate toxin-induced hepatic disorders including acute
liver injury, hepatitis… play a role in the hepatoprotection of phenolic-type Nrf2-activators and …

… prominent antioxidant and anti-inflammatory effects, and plays an important role in ameliorating
… , at least in part, via activation of Nrf2 and Nrf2-driven antioxidant responses (29,30). …