… exhibits promise as a potential topical analgesic, the mechanistic basis of its peripheral …
that ketamine can also elicit a peripheral antinociceptive effect in rat paw PGE 2 -induced …

… activates nNOS, thus initiating the NO/cGMP pathway and … Ketamine (80 μg/paw) was
administered 2 hr 55 min after local … , and the plantar surface of the rat paw was collected. This …

… , these data suggest that systemic ketamine activates the NO-cGMP pathway to produce …
ketamine produces antinociception in the acetic acid-induced writhing and formalin tests in mice…

… without inducing hyperactivity in the rats in the present study. … quickly reverses deficits in
spine density via activating the … of l-arginine–nitric oxide-cyclic guanosine monophosphate …

… /NO/cGMP pathway is linked to the central and peripheral K + … could attenuate formalin-induced
pain in mice's paw by an … administration of formalin in mice can locally activate NOS …

… Briefly, the rats were anesthetized with ketamine (60 mg/kg, IP) … of formalin in mice may locally
activate NOS and increase … in an increase in the cyclic guanosine monophosphate (cGMP) …

… induced by morphine or carbachol and the L-arginine-nitric … of the rat by the nitric oxide-cyclic
guanosine monophosphate … Oral ketamine and transdermal nitroglycerin as analgesic …

… stimuli was measured in Swiss mice using the Randall and … ketamine in activating the
neuronal nitric oxide synthase (nNOS) enzyme to produce antinociception via the L-arginine/nitric …

… 1 cannabinoid receptor activation in inflammatory conditions. … the nitric oxide/cyclic guanosine
monophosphate/adenosine … , in rat paw tissues after ketamine-induced counteraction of …

… the paw of mice. Taken together, these data suggest that the … is related to the activation of
the nitric oxide/cyclic guanosine … intraperitoneal injection of 10 % ketamine (Cayman Chemical) …