… killing of rat thymus cells in a final volume of 0.2 ml RPMI 1640 adenocarcinoma 13762 by
anti-tumor CD4/ T cells … ), anti-tumor T cell clones could recognize and kill tumor in situ (Fig.3).…

… reactivity with unmodified tumor in vitro, antitumor properties may … ified 13762 express cell
surface MHC class I1 molecules, … have been reported to express MHC class I1 in situ in certain …

… The anti-tumor effects of the CD4+ T cells required the presence of both MHC class I and class
II on host cells, … These results indicate that the apparent inability of tumor cells expressing …

… Ags in the context of cell surface MHC class I1 molecules. The … killing of tumor in situ by CD4'
T cells would require tumor … T-cell subsets in anti-tumor responses. Immunol. Today 8:267. …

… irradiated cognate 13762 tumor requires functional CD4+ T cells (23). … cell surface MHC
class I molecules are expressed, 13762 … in situ) or provide help for other cytolytic effector cells. …

… . Killing of rat adenocarcinoma 13762 in situ by adoptive transfer of CD4 + anti-tumor T
cells requires tumor expression of cell surface MHC class II molecules. …

… with 13762 cells elicits a turnor-specific protective anti-tumor … Expression of TGF in situ by
13762 tumor is considered likely… M., Elimination of cycling CD4" suppressor T cells with an anti-…

… then surface stained with Abs to human CD45, CD3, and CD4 … microenvironment the cellular
and molecular events associated … . Rat mammary adenocarcinoma 13762 expressing IFN-γ …

… with 13762 cells elicits a turnor-specific protective anti-tumor … Expression of TGF in situ by
13762 tumor is considered likely… M., Elimination of cycling CD4" suppressor T cells with an anti-…

… T cells play a central role as immune effectors, CD4+ T cells act to control the activation and
persistence of the CD8+ T cell … required the de novo generation of P815AB-specific CD8+ T …