Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination

RK Suryawanshi, IP Chen, T Ma, AM Syed, N Brazer… - Nature, 2022 - nature.com
… of whether widespread Omicron infections could lead to future cross-variant protection, …
Here we show that without vaccination, infection with Omicron induces a limited humoral immune

Antibody affinity and cross-variant neutralization of SARS-CoV-2 Omicron BA. 1, BA. 2 and BA. 3 following third mRNA vaccination

L Bellusci, G Grubbs, FT Zahra, D Forgacs… - Nature …, 2022 - nature.com
… the vaccine-induced immunity. Therefore, it is critical to know the persistence of cross-reactive
immunity generated following SARS-CoV-2 vaccination … the BNT162b2 vaccine we did not

Limited cross-variant neutralization after primary Omicron infection: consideration for a variant-containing booster

H Marcotte, L Hammarström… - Signal Transduction and …, 2022 - nature.com
SARS-CoV-2 Omicron variant has presented a severe threat to the effectiveness of vaccines
… al. demonstrated that Omicron infection boosts preexisting immunity induced by COVID-19 …

Pre-Omicron vaccine breakthrough infection induces superior cross-neutralization against SARS-CoV-2 Omicron BA. 1 compared to infection alone

ES da Silva, M Kohnen, G Gilson, T Staub… - International Journal of …, 2022 - mdpi.com
SARS-CoV-2 variants continuously mold the pandemic … elude immunity conferred by prior
infection or by vaccines readily … we could not confirm the role of time between vaccination and …

… infection after inactivated vaccine induced robust antibody responses and cross-neutralization of SARS-CoV-2 variants, but less immunity against Omicron

N Suntronwong, R Yorsaeng, J Puenpa, C Auphimai… - Vaccines, 2022 - mdpi.com
Immune response of individuals with SARS-CoV-2 breakthrough infection (CV + CV + Infection)
was compared to those with fully vaccinated CoronaVac vaccines without infection (CV + …

SARS-CoV-2 Omicron variants: burden of disease, impact on vaccine effectiveness and need for variant-adapted vaccines

S Pather, SA Madhi, BJ Cowling, P Moss… - … in immunology, 2023 - frontiersin.org
… group of variants forms a new phylogenetically distinct clade that is not directly descended
from other SARS-CoV-2 VOCs (9) (Figure 1). Of all the previous VOCs, BA.1 is most closely …

Omicron variant of SARS-COV-2 infection elicits cross-protective immunity in people who received boosters or infected with variant strains

S Chowdhury, MS Chowdhury… - International …, 2022 - journals.sagepub.com
cross-variant neutralization in vaccinated people. Their findings suggest that Omicron infection
boosts preexisting vaccine… may or may not have prior immunity against SARS-CoV-2. This …

… 19 vaccination on humoral immunity 3 months after sars-Cov-2 omicron infection and booster effect of a fourth covid-19 vaccination 2 months after sars-Cov-2 omicron …

J Kim, H Seo, HW Kim, D Kim, HJ Kwon, YK Kim - Viruses, 2022 - mdpi.com
not been previously vaccinated and were infected with the Omicron variant developed only
limited … Our study results showing differences in cross-variant immunity from Omicron variant …

The fourth vaccination with a non-SARS-CoV-2 variant adapted vaccine fails to increase the breadth of the humoral immune response

S Hein, C Sabino, NI Benz, E Görgülü, TJ Maier… - Scientific Reports, 2023 - nature.com
… antibodies and broaden the immune response against the SARS-CoV-2 Delta and Omicron
variant, we … there is no impact on in the baseline titer against the Omicron or Delta variant. …

[PDF][PDF] Vaccine-induced spike-and nucleocapsid-specific cellular responses maintain potent cross-reactivity to SARS-CoV-2 Delta and Omicron variants

F Chiuppesi, JA Zaia, K Faircloth, D Johnson, M Ly… - IScience, 2022 - cell.com
… of mutations in the Omicron S protein, it is not surprising that the … SARS-CoV-2-specific
humoral and cellular immune … confer potent cross-variant reactivity over a prolonged period after …