Live tularemia vaccine confers protection against lethal Legionella and Listeria infections in experimental animals

YF Belyi, IS Tartakovskii… - FEMS Immunology & …, 1996 - academic.oup.com
… toward experimental legionellosis and listeriosis was studied… Immunisation with tularemia
vaccine protected over 80% and 17% of experimental animals against subsequent lethal

Recombinant attenuated Listeria monocytogenes vaccine expressing Francisella tularensis IglC induces protection in mice against aerosolized Type A F. tularensis

Q Jia, BY Lee, DL Clemens, RA Bowen, MA Horwitz - Vaccine, 2009 - Elsevier
… intracellular pathogens, including Legionella pneumophila, … tularensis protein IglC (rLm/iglC)
are protected against lethal … expressing IglC or KatG could protect animals against higher …

Development, Strategies, and Challenges for Tularemia Vaccine

S Moradkasani, M Maurin, AS Farrokhi, S Esmaeili - Current Microbiology, 2024 - Springer
… such as Salmonella, Brucella, Legionella, and Yersinia spp. has … -12 conferred complete
protection against LVS challenge. This … as vaccines against tularemia in various animal models (…

Live tularemia vaccine but not proteins purified from Francisella tularensis can confer protection against lethal Listeria infection in mice

YF Belyi, VV Petrosov, IS Tartakovskii, YG Suchkov - Apmis, 1995 - Wiley Online Library
Bacteria used in our experiments included strain NCTC 7973 … Legionella pneumophila and
different species of Legionella. … vaccine against lung infection by Legionella pneumophila. Zh…

Tularemia in BALB/c and C57BL/6 mice vaccinated with Francisella tularensis LVS and challenged intradermally, or by aerosol with virulent isolates of the pathogen …

W Chen, H Shen, A Webb, R KuoLee, JW Conlan - Vaccine, 2003 - Elsevier
… microabrasions when handling infected animal carcasses, via … tularensis routinely cause
lethal infection in people … the degree of protective immunity conferred by vaccination with F. …

Nature of Protective Immunity to Francisella tularensis

A Tärnvik - Reviews of infectious diseases, 1989 - academic.oup.com
… Autopsies in fatal cases of tularemia in humans have disclosed … effect against tularemia in
several experimental animals and that … A similar protective effect was conferred by transfer of …

TolC-dependent modulation of host cell death by the Francisella tularensis live vaccine strain

CR Doyle, JA Pan, P Mena, WX Zong… - Infection and …, 2014 - Am Soc Microbiol
… causes a lethal infection in mice that mimics human tularemia, … An additional species of
Francisella, F. novicida, has low … Multidrug efflux pumps confer resistance to a range of detergents…

Role of Innate Host Defenses in Acute and Vaccination Models of Pneumonic Tularemia

D Schmitt - 2012 - d-scholarship.pitt.edu
… : acute infection of naïve animals with a type A strain and after vaccination with the live
vaccinetularensis results in the potentially fatal illness, tularemia. Less than 10 organisms can …

Francisella tularensis vaccines

KF Griffin, PCF Oyston, RW Titball - FEMS Immunology & …, 2007 - academic.oup.com
… may occasionally prove to be fatal, tularaemia is essentially a … animals developed many of
the clinical signs of infection after … tularensis, but can confer protection against low-virulence …

Working toward the Future: Insights into Francisella tularensis Pathogenesis and Vaccine Development

RD Pechous, TR McCarthy… - … and molecular biology …, 2009 - Am Soc Microbiol
… major properties of several Francisella species, including F. … Coxiella burnetii and
Legionella pneumophila (109). F. … in a Listeria monocytogenes ΔactA mutant confers protection