MAP 30: a new inhibitor of HIV-1 infection and replication
S Lee-Huang, PL Huang, PL Nara, HC Chen, H Kung… - FEBS letters, 1990 - Elsevier
… MAP 30 inhibits both infection and replication of HIV-1. Treatment of HIVinfected individuals
with MAP 30 may block further depletions of CD4-T cells and inhibit viral replication. Such …
with MAP 30 may block further depletions of CD4-T cells and inhibit viral replication. Such …
[引用][C] MAP 30: a new inhibitor of HIV-1 infection and replication [from Momordica charantia seeds and fruits].
S Lee-Huang, PL Huang, PL Nara, HC Chen, HF Kung… - 1990 - cabidigitallibrary.org
… Distribution Maps of Plant Diseases Distribution Maps of Plant Pests … Distribution Maps
of Plant Diseases …
of Plant Diseases …
[HTML][HTML] Solution structure of anti-HIV-1 and anti-tumor protein MAP30: structural insights into its multiple functions
YX Wang, N Neamati, J Jacob, I Palmer, SJ Stahl… - Cell, 1999 - cell.com
… inhibition of HIV-1 infection in lymphocytes and monocytes, and viral replication in HIV-infected …
At 30 kDa, MAP30 is among the largest single-chain proteins whose solution structures …
At 30 kDa, MAP30 is among the largest single-chain proteins whose solution structures …
[HTML][HTML] The critical role of p38 MAP kinase in T cell HIV-1 replication
PS Cohen, H Schmidtmayerova, J Dennis… - Molecular …, 1997 - Springer
… MAP kinase activation has been implicated in HIV-1 infection … this compound could inhibit
HIV-1 replication in primary T … and reactivation of latent HIV-1-infected monocytic cells (30). Our …
HIV-1 replication in primary T … and reactivation of latent HIV-1-infected monocytic cells (30). Our …
Suppression of HIV-1 viral replication and cellular pathogenesis by a novel p38/JNK kinase inhibitor
K Muthumani, SA Wadsworth, NS Dayes, DS Hwang… - Aids, 2004 - journals.lww.com
… MAP) kinase superfamily of signal transduction molecules may play an important role in HIV-1
infection… concentration (IC 50 ) 20–30 nM] and is reported to be approximately 10-fold less …
infection… concentration (IC 50 ) 20–30 nM] and is reported to be approximately 10-fold less …
Inhibition of the integrase of human immunodeficiency virus (HIV) type 1 by anti-HIV plant proteins MAP30 and GAP31.
S Lee-Huang, PL Huang, PL Huang… - Proceedings of the …, 1995 - National Acad Sciences
… as well as replication of the virus in alreadyinfected cells. … agents exhibit dose-dependent
inhibition of HIV-1 integrase. … that plant proteins MAP30 (Momordica anti-HIV protein of 30 kDa) …
inhibition of HIV-1 integrase. … that plant proteins MAP30 (Momordica anti-HIV protein of 30 kDa) …
Anti-HIV and anti-tumor activities of recombinant MAP30 from bitter melon
S Lee-Huang, PL Huang, HC Chen, PL Huang… - Gene, 1995 - Elsevier
… MAP30 (re-MAP30) and to determine its anti-HIV, anti-tumor and other activities. We report
here that re-MAP30 … and Huang, PL: MAP 30: a new inhibitor of HIV-1 infection and replication…
here that re-MAP30 … and Huang, PL: MAP 30: a new inhibitor of HIV-1 infection and replication…
Inhibition of HIV-1 by fusion inhibitors
D Eggink, B Berkhout… - Current pharmaceutical …, 2010 - ingentaconnect.com
… This approach requires the accurate mapping of residues … peptide, but with a half-life of over
30 hours [67]. Cholesterol … high systemic drug levels to inhibit HIV-1 replication. A different …
30 hours [67]. Cholesterol … high systemic drug levels to inhibit HIV-1 replication. A different …
Anti-HIV agent MAP30 modulates the expression profile of viral and cellular genes for proliferation and apoptosis in AIDS-related lymphoma cells infected with …
Y Sun, PL Huang, JJ Li, YQ Huang, L Zhang… - Biochemical and …, 2001 - Elsevier
… HIV-1 and AIDS-related tumors infected with the KS virus. … of viral genes that promote viral
replication, specific cellular genes … MAP 30 downregulates the expression of these genes. …
replication, specific cellular genes … MAP 30 downregulates the expression of these genes. …
[HTML][HTML] Modulation of HIV‐1 infectivity by MAPK, a virion–associated kinase
JM Jacqué, A Mann, H Enslen, N Sharova… - The EMBO …, 1998 - embopress.org
… is less sensitive to inhibitors of the MAP kinase pathway. … in this study do not require Vif to
support virus replication. … Following incubation at 30C for 30 min, the reactions were stopped …
support virus replication. … Following incubation at 30C for 30 min, the reactions were stopped …