… monitoring of these changes in patients and better monitoring of their reaction to treatment. …
progression and therapeutic response. Tracking a patient's response to therapy through short-…

… At the time of the present study, the RANO criteria [7] had been updated with modified
radiological definitions for evaluation of tumor progression in malignant gliomas. This includes the …

… malignant transformation. 2HG represents an ideal biomarker to probe treatment response in
IDH-mutant glioma patients… resonance spectroscopy (MRS) as a result of antitumor therapy. …

… to more generally as the “parametric response map” (PRM), … of WHO grade 3 and 4 glioma
patients that was designed to … composite metrics of early treatment response as assessed 3 …

… therapy is thought to be due largely to underlying tumor molecular and genomic heterogeneity,
which leads to differential treatment responses and patient … maintenance of glioma stem …

… delivery and the effect of the BBB on treatment response at the … to essentially any novel
therapeutic strategy targeting GBM … measured in a rat glioma model. Average concentration of …

… for early treatment response. VHLs were evaluated as biomarker maps of neovascularization
… changes in glioma and other brain pathologies as well as on therapy monitoring. However, …

… treatment response, limited to a more homogenous population of patients with high-grade
glioma… A total of 34 patients with malignant glioma were enrolled in this study and available for …

… that the diagnosis of early stages of malignant glioma can be aided with DWI, such that …
maps for two patients, one with a grade II tumor and another with a glioblastoma (grade IV glioma)…

… This same region of interest was then mapped to all subsequent scans of the same patient.
… of assessing malignancy and of monitoring the treatment response of malignant gliomas. On …