Mass spectrometric quantification of urinary 6-sulfatoxymelatonin: age-dependent excretion and biological variation

M van Faassen, A van der Veen… - Clinical Chemistry and …, 2021 - degruyter.com
age-dependent 24-h excretion of 6-sulfatoxymelatonin into … investigate the excretion of
6-sulfatoxymelatonin into urine in a … biological variation of urinary 6-sulfatoxymelatonin excretion. …

Factors influencing urinary 6‐sulphatoxymelatonin, a major melatonin metabolite, in normal human subjects

CJ Bojkowski, J Arendt - Clinical endocrinology, 1990 - Wiley Online Library
… We report here an extended assessment of aMT6s excretion … a gas chromatography-mass
spectrometry (GCMS) method … its metabolite, 6-sulfatoxymelatonin. Clinical Chemisrry, 33, …

[HTML][HTML] Simultaneous determination of melatonin and 6-hydroxymelatonin in human overnight urine by LC-MS/MS

G Magliocco, F Le Bloc'h, A Thomas… - … of Chromatography B, 2021 - Elsevier
mass spectrometry (LC-MS/MS) has been developed. … would require the synthesis of 6-sulfatoxymelatonin
and 6-… al. measured a nocturnal urinary melatonin excretion rate over a …

[PDF][PDF] Comparative study of stable isotope-labeled internal standard substances for the LC-MS/MS determination of the urinary excretion of melatonin

H Shimazaki, S Ogawa, H Takano, S Ohki… - … mass spectrometry, 2023 - jsbms.jp
… In contrast, hydrolysis of 6-S-MEL and 6-GMEL in urine to 6-O-MEL via … determination of
the total excreted amount of 6-OMEL in urine via gas chromatography‒mass spectrometry or LC-…

… of multiple reaction monitoring cubed performed by a quadrupole-linear ion trap mass spectrometer for quantitative determination of 6-sulfatoxymelatonin in urine

LV Lopukhov, AV Balandina, LS Nigmatullina… - … of Chromatography B, 2022 - Elsevier
6-sulfatoxymelatonin (6-SM) is considered as the main metabolite of melatonin excreted
in the urine, and there is a strong correlation between the concentrations of 6-SM in …

Estimation of reference curves for the urinary steroid metabolome in the first year of life in healthy children: tracing the complexity of human postnatal steroidogenesis

NA Dhayat, AC Frey, BM Frey, CH d'Uscio… - … and molecular biology, 2015 - Elsevier
mass spectrometry (GC–MS) and steroid concentrations corrected for urinary creatinine
excretion … We obtained explicit, flexible, smooth and robust age-dependent and sex-dependent …

Melatonin secretion and its rhythms in biological fluids

SF Pang, PPN Lee, YS Chan, EA Ayre - Melatonin, 2020 - taylorfrancis.com
… methods such as gas chromatography-mass spectrometry (GCMS), 1 … secretion of
melatonin and excretion of 6-sulfatoxymelatonin … Iguchi, H., Kato, K., and lbayashl, H., Age-dependent

The basic physiology and pathophysiology of melatonin

B Claustrat, J Brun, G Chazot - Sleep medicine reviews, 2005 - Elsevier
excreted in urine as sulphate and, to a lesser extent, as glucuronide conjugates. Urine 6-sulfatoxymelatonin
(aMT6S) excretion … the temperature profile determination. Study conditions (…

Melatonin: Aeromedical, Toxicopharmacological, and Analytical Aspects,

DC Sanders, AK Chaturvedi… - Journal of analytical …, 1999 - academic.oup.com
… gas chromatography-mass spectroscopy analytical techniques. … of conjugated 6-hydroxymelatonin
(6-sulfatoxymelatonin) … Age-dependent reduction in serum melatonin concentrations …

Age-related attenuation of the evening circadian arousal signal in humans

M Münch, V Knoblauch, K Blatter, C Schröder… - Neurobiology of …, 2005 - Elsevier
… by gas chromatography–mass spectroscopy with an analytical … The study provides quantitative
evidence for an age-dependentsecretion in our older group was decreased during the …