Mechanism of the antitumor and radiosensitizing effects of a manganese porphyrin, MnHex-2-PyP
SW Shin, C Choi, GH Lee, A Son, SH Kim… - Antioxidants & redox …, 2017 - liebertpub.com
… -porphyrin-driven inhibition of other MAPKs found in this work, giving rise to strong
radiosensitization. … of the molecular pathways behind the effects of Mn-porphyrin-based SOD …
radiosensitization. … of the molecular pathways behind the effects of Mn-porphyrin-based SOD …
Metalloporphyrins: Radioprotector and Radiosensitizer
Y Alzarie, O Badary, S Nofal - Journal of Advanced Pharmacy …, 2021 - journals.ekb.eg
… Three lead manganese porphyrins compounds have been … -2-PyP5+ showed antitumor
effect by itself and in combination … cells to IR and the underlying mechanisms of this process. In …
effect by itself and in combination … cells to IR and the underlying mechanisms of this process. In …
[HTML][HTML] H2O2-Driven Anticancer Activity of Mn Porphyrins and the Underlying Molecular Pathways
I Batinic-Haberle, A Tovmasyan, Z Huang… - … medicine and cellular …, 2021 - hindawi.com
… The tumor radiosensitizing effect of MnP was discussed with … studies, we only looked at the
anticancer effect of MnTE-2-PyP5… fully comprehend the mechanism of the anticancer action of …
anticancer effect of MnTE-2-PyP5… fully comprehend the mechanism of the anticancer action of …
Mn porphyrin-based redox-active drugs: differential effects as cancer therapeutics and protectors of normal tissue against oxidative injury
I Batinic-Haberle, A Tovmasyan… - Antioxidants & redox …, 2018 - liebertpub.com
… Anticancer actions of Mn porphyrins … The data implicated the inhibition of NF-jB activity as
a mechanism of … model, Park’s team showed the radiosensitizing effect of MnTnHex2-PyP5+ (…
a mechanism of … model, Park’s team showed the radiosensitizing effect of MnTnHex2-PyP5+ (…
Manganese porphyrin and radiotherapy improves local tumor response and overall survival in orthotopic murine mammary carcinoma models
MK Boss, RE Oberley-Deegan… - Radiation …, 2021 - meridian.allenpress.com
… compounds, known as manganese porphyrins (MnPs), have … studies have focused on local
effects of MnPs and radiation; … that these primary tumor treatment effects would result in a …
effects of MnPs and radiation; … that these primary tumor treatment effects would result in a …
[HTML][HTML] A Redox-active Mn Porphyrin, MnTnBuOE-2-PyP5+, Synergizes with Carboplatin in Treatment of Chemoresistant Ovarian Cell Line
L Chaiswing, C Yarana, W St Clair… - … Medicine and Cellular …, 2022 - hindawi.com
… Choi, GH Lee et al., “Mechanism of the antitumor and radiosensitizing effects of a
manganese porphyrin, MnHex-2-PyP,” Antioxidants & Redox Signaling, vol. 27, no. 14, pp. …
manganese porphyrin, MnHex-2-PyP,” Antioxidants & Redox Signaling, vol. 27, no. 14, pp. …
[HTML][HTML] CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic …
D Leu, I Spasojevic, H Nguyen, B Deng, A Tovmasyan… - Redox biology, 2017 - Elsevier
… Mn porphyrin (MnP)-based redox active drugs have demonstrated differential effects on
cancer and normal tissues in experimental animals that lead to protection of normal tissues and …
cancer and normal tissues in experimental animals that lead to protection of normal tissues and …
MnTnHex-2-PyP5+, Coupled to Radiation, Suppresses Metastasis of 4T1 and MDA-MB-231 Breast Cancer via AKT/Snail/EMT Pathways
SW Shin, C Choi, H Kim, Y Kim, S Park, SY Kim… - Antioxidants, 2021 - mdpi.com
… the mechanism of action of Mn porphyrins … effect demonstrated in previous studies [25].
We anticipate that the insights into the anticancer and antimetastatic potentials of Mn porphyrins …
We anticipate that the insights into the anticancer and antimetastatic potentials of Mn porphyrins …
Radiation-mediated tumor growth inhibition is significantly enhanced with redox-active compounds that cycle with ascorbate
A Tovmasyan, JC Bueno-Janice… - Antioxidants & redox …, 2018 - liebertpub.com
… activity of Mn porphyrins is critical for their anticancer effects and is … of the moderate SOD-like
activity of released manganese. … of MnE/Asc and MnBuOE/Asc on tumor radiosensitization. …
activity of released manganese. … of MnE/Asc and MnBuOE/Asc on tumor radiosensitization. …
[HTML][HTML] MnTE-2-PyP Attenuates TGF-β-Induced Epithelial-Mesenchymal Transition of Colorectal Cancer Cells by Inhibiting the Smad2/3 Signaling Pathway
Y Yang, P Zhang, R Yan, Q Wang, E Fang… - … medicine and cellular …, 2019 - hindawi.com
… Taken together, we provide an in-depth mechanism by which MnTE-2-PyP inhibits …
Mechanism of the antitumor and radiosensitizing effects of a manganese porphyrin, MnHex-2-PyP…
Mechanism of the antitumor and radiosensitizing effects of a manganese porphyrin, MnHex-2-PyP…