Mechanisms of disease: hepatic steatosis in type 2 diabetes—pathogenesis and clinical relevance
M Roden - Nature clinical practice Endocrinology & metabolism, 2006 - nature.com
… in the formation of liver glycogen, as … liver is termed hepatic steatosis. Absence of both
significant alcohol consumption and other liver disease is the criterion for defining simple hepatic …
significant alcohol consumption and other liver disease is the criterion for defining simple hepatic …
[HTML][HTML] Nonalcoholic fatty liver disease and type 2 diabetes: Pathophysiological mechanisms shared between the two faces of the same coin
C Acierno, A Caturano, PC Pafundi… - Exploration of …, 2020 - explorationpub.com
… hepatic steatosis is a phenotype that recognizes diverse and complex causes and a wide
spectrum of clinical … or without T2DM, supports the clinical relevance of such a mechanism [51]. …
spectrum of clinical … or without T2DM, supports the clinical relevance of such a mechanism [51]. …
Metabolic liver disease in diabetes–from mechanisms to clinical trials
… mechanisms underlying T2DM and NAFLD, the relevance of … of subgroups at specific risk
of disease progression. Also, the … , liver steatosis could be associated with hepatic insulin …
of disease progression. Also, the … , liver steatosis could be associated with hepatic insulin …
[HTML][HTML] Non-alcoholic fatty liver disease (NAFLD), type 2 diabetes, and non-viral hepatocarcinoma: Pathophysiological mechanisms and new therapeutic strategies
E Vetrano, L Rinaldi, A Mormone, C Giorgione… - Biomedicines, 2023 - mdpi.com
… hepatic steatosis progression through several mechanisms, … apoptosis, in a fatty liver than
in a healthy liver. In addition, a … importance of Tregs in NAFLD and NASH, providing clinical …
in a healthy liver. In addition, a … importance of Tregs in NAFLD and NASH, providing clinical …
Non-alcoholic fatty liver disease in type 2 diabetes: pathogenesis and treatment options
K Tziomalos, VG Athyros… - Current vascular …, 2012 - ingentaconnect.com
… and T2DM is of paramount importance for the reduction of the … for hepatic steatosis and
non-alcoholic fatty liver disease in … 2E1 in non-alcoholic fatty liver disease: mechanisms and …
non-alcoholic fatty liver disease in … 2E1 in non-alcoholic fatty liver disease: mechanisms and …
Diabetes and nonalcoholic fatty liver disease: a pathogenic duo
KH Williams, NA Shackel, MD Gorrell… - Endocrine …, 2013 - academic.oup.com
… NAFLD predicts the development of type 2 diabetes and vice … through specific pathogenic
mechanisms. In particular, … extensively in articles addressing diabetes pathogenesis (7, 8…
mechanisms. In particular, … extensively in articles addressing diabetes pathogenesis (7, 8…
[HTML][HTML] Potential nexus of non-alcoholic fatty liver disease and type 2 diabetes mellitus: insulin resistance between hepatic and peripheral tissues
W Mu, X Cheng, Y Liu, Q Lv, G Liu, J Zhang… - Frontiers in …, 2019 - frontiersin.org
… paradigm regarding the pathological mechanisms of liver metabolism in NAFLD and … hepatic
steatosis and lipid-induced hepatic insulin resistance. It is also of great clinical importance …
steatosis and lipid-induced hepatic insulin resistance. It is also of great clinical importance …
Investigating the pathogenesis and risk of Type 2 diabetes: clinical applications of metabolomics
… these studies may be more relevant to the human disease. Indeed, the … The precise
mechanisms that underscore … to the development of IR and diabetes pathogenesis remains …
mechanisms that underscore … to the development of IR and diabetes pathogenesis remains …
Understanding the mechanisms of reversal of type 2 diabetes
… summarise the studies relevant to the understanding of type 2 diabetes as a reversible clinical
state. … Because hepatic steatosis is now the most common cause of moderately raised ALT …
state. … Because hepatic steatosis is now the most common cause of moderately raised ALT …
[HTML][HTML] Liver cirrhosis and diabetes: risk factors, pathophysiology, clinical implications and management
D Garcia-Compean, JO Jaquez-Quintana… - World journal of …, 2009 - ncbi.nlm.nih.gov
… of importance in the occurrence of glucose metabolic disorders… liver cirrhosis is higher than
in type 2 DM, and impairment of hepatic insulin degradation may be an important mechanism …
in type 2 DM, and impairment of hepatic insulin degradation may be an important mechanism …