Mice lacking cystathionine beta synthase have lung fibrosis and air space enlargement
J Hamelet, N Maurin, R Fulchiron, JM Delabar… - … and molecular pathology, 2007 - Elsevier
… fibrosis but also with pulmonary fibrosis in severe hyperhomocysteinemia. Pulmonary fibrosis
has … that CBS deficiency in mice induces extensive pulmonary fibrosis independently of …
has … that CBS deficiency in mice induces extensive pulmonary fibrosis independently of …
The H2S-generating enzymes cystathionine β-synthase and cystathionine γ-lyase play a role in vascular development during normal lung alveolarization
A Madurga, A Golec, A Pozarska… - … of Physiology-Lung …, 2015 - journals.physiology.org
… exposure, namely, alveolar growth was improved and pulmonary hypertension was limited.
… partially restored alveolar growth in hyperoxia-exposed mouse pups, stimulated epithelial …
… partially restored alveolar growth in hyperoxia-exposed mouse pups, stimulated epithelial …
The role of cystathionine-γ-lyase in blunt chest trauma in cigarette smoke exposed mice
C Hartmann, S Hafner, A Scheuerle, P Möller… - Shock, 2017 - journals.lww.com
… CSE −/− mice without CS exposure showed higher cytokine and chemokine levels, and this
… In conclusion, in murine acute-on-chronic pulmonary disease, CSE knockout aggravated …
… In conclusion, in murine acute-on-chronic pulmonary disease, CSE knockout aggravated …
Endothelial Dysfunction and Elevation of S-Adenosylhomocysteine in Cystathionine β-Synthase–Deficient Mice
S Dayal, T Bottiglieri, E Arning, N Maeda… - Circulation …, 2001 - Am Heart Assoc
… Homozygous CBS-deficient mice were not studied because they exhibit growth retardation,
… +/– mice without folate deficiency. The development of endothelial dysfunction in mice was …
… +/– mice without folate deficiency. The development of endothelial dysfunction in mice was …
Gasping for sulfide: a critical appraisal of hydrogen sulfide in lung disease and accelerated aging
… −/− mice manifested fibrotic injuries and air space enlargement in the lungs, with increased
… most for up to 5 weeks after birth with severe growth retardation (225). However, Hamelet et …
… most for up to 5 weeks after birth with severe growth retardation (225). However, Hamelet et …
[HTML][HTML] Supersulphides provide airway protection in viral and chronic lung diseases
T Matsunaga, H Sano, K Takita, M Morita… - Nature …, 2023 - nature.com
… lungs and in chronic lung diseases, including chronic obstructive pulmonary disease (COPD),
idiopathic pulmonary fibrosis (… growth in the lung significantly increased in Cars2 +/− mice …
idiopathic pulmonary fibrosis (… growth in the lung significantly increased in Cars2 +/− mice …
Hydrogen sulfide ameliorates tobacco smoke-induced oxidative stress and emphysema in mice
… role in the pathogenesis of chronic obstructive pulmonary disease (COPD). In the present …
Alveolar enlargement and destruction were quantified by the mean linear intercept (Lm) in …
Alveolar enlargement and destruction were quantified by the mean linear intercept (Lm) in …
The role of hydrogen sulfide in normal and aberrant late lung development
A Madurga Hernández - 2015 - jlupub.ub.uni-giessen.de
… Bronchopulmonary dysplasia (BPD) is a chronic lung disease … as a mediator of lung physiology
and disease. In this study, … Clinical examples of such perturbation of normal lung growth …
and disease. In this study, … Clinical examples of such perturbation of normal lung growth …
[HTML][HTML] Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment
KN Maclean, J Sikora, V Kožich, H Jiang… - Molecular genetics and …, 2010 - Elsevier
… /−) mice that had survived into adulthood, we found that the livers of these mice were severely
enlarged and … the presence of pulmonary fibrosis in this cbs (−/−) model [21] indicating that …
enlarged and … the presence of pulmonary fibrosis in this cbs (−/−) model [21] indicating that …
Cardiopulmonary, histologic, and inflammatory effects of intravenous Na2S after blunt chest trauma-induced lung contusion in mice
F Wagner, A Scheuerle, S Weber, B Stahl… - Journal of Trauma …, 2011 - journals.lww.com
… lung burn injury, 2 and mice lacking CBS presented with early fibrosis and airway enlargement…
-inflammatory effects 29 and thereby modulates lung injury: in mice in vivo, inhalation of …
-inflammatory effects 29 and thereby modulates lung injury: in mice in vivo, inhalation of …