… microvascular proliferative growth occurs significantly more often in clinically defined high-flow
vascular malformations … symptomatic AVMs, we found areas of microvascular proliferation …

… but high flow feeding arteries harboring perinidal or … revealed acute inflammation in
arteriovenous malformations (… and AVM characteristics which predispose specific lesions to one …

… destabilize these lesions to develop novel medical therapies, … large caliber, high-flow AV
shunt into capillary-like vessels. … presentation, embolized versus nonembolized lesions, and …

… As this finding questions the previous definition, the primary … chronic inflammation in high-flow
lesions than in low-flow lesions, … 1 low flow was embolized and showed no proliferation. …

… These high flow lesions can vary in size and location. … that increased flow in a microvascular
bed can cause capillaries to … In an inflammatory environment, the extracellular domain of …

… patterns, particularly in high-flow malformations: here, the … If there is any concomitant
inflammation or infection of the LM… to study the microvascular circulation of vascular malformations. …

… It is hypothesized that microvessel formation through … shown to contribute to the anti-inflammatory
and anti-tumor effects of … To mimic the mechanical stress on high-flow malformations a …

… , and/or high-flow direct AV shunts through embolization. … embolization when applied to
larger, more complex lesions. … We have identified inflammatory genes associated with risk of …

… , inflammation has been suggested to contribute to lesion … Arteriovenous malformations
(AVMs) are high-flow, low-… -9 levels and decreased cerebro-microvessel density [295]. A small …

… lesion affecting the upper lip (arrow) with painful swelling. (b) … to convert a high-flow lesion
to a lower-flow lesion, which is … , we recommend endovascular treatment with embolization …