… We found that at a concentration of 30μM, tetracycline, doxycycline, and minocycline …
doxycycline and minocycline in the R6/2 mouse. Although we achieved brain levels of minocycline …

… Minocycline and doxycycline were dissolved in NaCl 0.9%. Fresh solutions were prepared
each day before injections. The volume injected was adjusted according to the body weight …

… ), the administration of minocycline was associated with the delay of disease progression.
In … huntingtin by minocycline and doxycycline was not associated with beneficial effects in …

… of minocycline in the R6/2 transgenic model of Huntington’s disease (HD), this tetracycline
has been re-evaluated in another model, the N171-82Q strain. Ten miligrams per kilogram …

… (iNOS), and has been shown to delay disease progression in the mouse model R6/2 of …
Minocycline was well tolerated during this study period and no serious adverse events were …

… -generation tetracyclines, such as MC and doxycycline, have a higher penetration into …
model of PD by directly inhibiting MPTP/MPP + -induced glial expression or directly inhibiting NO-…

… in R6/2 mice administered with minocycline or doxycycline, although they showed a signifi…
minocycline showed no benefit over placebo in any tested measure, although there were no …

… penetrates the CSF of human beings better than doxycycline … effects of minocycline in various
models of neurological disease, … the efficacy of minocycline in Huntington's disease. In this …

… apoptosis in models of Huntington's disease, amyotrophic lateral sclerosis and Parkinson's
… trials, minocycline should be preferred to doxycycline to combine the beneficial properties of …

… In conclusion, minocycline exerts neuroprotective effects in rodent models of … that are not
conducive for publication. Compared with another tetracycline (doxycycline), minocycline is …