Modulation of CGRP-induced light aversion in wild-type mice by a 5-HT1B/D agonist

EA Kaiser, A Kuburas, A Recober… - Journal of …, 2012 - Soc Neuroscience
… of rizatriptan, a 5-HT 1B/D agonist anti-… light aversion in wild-type (WT) C57BL/6J mice. This
strategy builds on our finding that CGRP could induce light aversion in nestin/hRAMP1 mice

PACAP induces light aversion in mice by an inheritable mechanism independent of CGRP

A Kuburas, BN Mason, B Hing, AS Wattiez… - Journal of …, 2021 - Soc Neuroscience
mice. Importantly, an anti-PACAP monoclonal antibody could block PACAP-induced light
aversion but not CGRP-induced light aversion. … involved in pain modulation. These include the …

Induction of migraine-like photophobic behavior in mice by both peripheral and central CGRP mechanisms

BN Mason, EA Kaiser, A Kuburas… - Journal of …, 2017 - Soc Neuroscience
… CNS, we used CGRP-induced light-aversive behavior in mice as a … in light-aversive behavior
in wild-type CD1 mice similar to … migraine drugs, the 5-HT 1B/D agonist sumatriptan and a …

Vascular actions of peripheral CGRP in migraine-like photophobia in mice

BN Mason, AS Wattiez, LK Balcziak, A Kuburas… - …, 2020 - journals.sagepub.com
… or just a correlative role in CGRP-induced light aversion, we used … Phenylephrine is a
potent and selective agonist of α-… only examined aversion to bright light in wild-type mice and …

CGRP induces migraine-like symptoms in mice during both the active and inactive phases

AS Wattiez, OJ Gaul, A Kuburas, E Zorrilla… - The journal of headache …, 2021 - Springer
… the validity of CGRP-induced behavioral changes in mice by … of migraine-like light aversion
and squint response in mice by CGRP is not … Dural administration of the TRPA1 agonist allyl …

[HTML][HTML] CGRP administration into the cerebellum evokes light aversion, tactile hypersensitivity, and nociceptive squint in mice

M Wang, TL Duong, BJ Rea, JS Waite… - Frontiers in Pain …, 2022 - frontiersin.org
… of CGRP induced similar light-aversive behaviors in wild-type … Fluorescein-15-CGRP is a
full CGRP receptor agonist but has less … that are modulated by CGRP in the MN are unknown. …

Investigating migraine-like behavior using light aversion in mice

M Wang, BN Mason, LP Sowers, A Kuburas… - JoVE (Journal of …, 2021 - jove.com
… with light aversion using transgenic nestin/hRAMP1 mice in … exhibit photophobia 11 , light
aversion is considered to be an … CGRP-induced light aversion in both CD1 and C57BL/6J …

[HTML][HTML] Stimulation of CGRP-expressing neurons in the medial cerebellar nucleus induces light and touch sensitivity in mice

M Wang, WC Castonguay, TL Duong, MW Huebner… - Neurobiology of …, 2022 - Elsevier
… strategy using Calca Cre/+ mice to drive Cre-dependent … migraine symptoms, including light
aversion, cutaneous allodynia, … decreased the time spent in the light, which was coupled to …

CGRP in animal models of migraine

AS Wattiez, M Wang, AF Russo - Calcitonin Gene-Related Peptide (CGRP …, 2019 - Springer
… -migraine drug is a 5-HT 1B and 5-HT 1D agonist that can prevent … described ip CGRP-induced
spontaneous pain in mice. The … of CGRP in wild-type mice induced light aversion when …

Trigeminal pain molecules, allodynia, and photosensitivity are pharmacologically and genetically modulated in a model of traumatic brain injury

BV Daiutolo, A Tyburski, SW Clark… - Journal of …, 2016 - liebertpub.com
… in iNOS KO mice and compared to wild-type CCI mice with … 5HT1B/1D receptor agonist with
a role in descending pain modulation. … Rizatriptan reduced CGRP-induced light aversion and …