Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives
F Andreoli, A Jorge Moura Barbosa… - … pharmaceutical …, 2013 - ingentaconnect.com
… various cancer types with epigenetic targets, considering that … that these targets are validated
for anticancer drug design purposes… of epigenetic targets, associating them to relevant drug …
for anticancer drug design purposes… of epigenetic targets, associating them to relevant drug …
Targeting epigenetics for cancer therapy
JW Park, JW Han - Archives of pharmacal research, 2019 - Springer
… structure with ubiquitin, they play distinctive epigenetic roles … in cancer, four anti-cancer drugs
that target these mechanisms … therapy can be another strategy for cancer drug development…
that target these mechanisms … therapy can be another strategy for cancer drug development…
[HTML][HTML] Histone modification and histone modification-targeted anti-cancer drugs in breast cancer: Fundamentals and beyond
J Feng, X Meng - Frontiers in Pharmacology, 2022 - frontiersin.org
… HMs have been extensively studied from diverse perspectives, … the development of epi-drugs
that target epigenetic modulators. … transfer mechanisms and structural homology (Table 2). …
that target epigenetic modulators. … transfer mechanisms and structural homology (Table 2). …
Genetic and epigenetic modulation of drug resistance in cancer: challenges and opportunities
… , making them suitable targets for drug development. In addition, … promises of targeting DDR
pathways for anticancer therapy. … : clinicopathological relevance, structural data and drug …
pathways for anticancer therapy. … : clinicopathological relevance, structural data and drug …
Potential of epigenetic therapies in the management of solid tumors
V Valdespino, PM Valdespino - Cancer management and research, 2015 - Taylor & Francis
… for future epigenetic drug discovery and development. More … of epigenetic targets for
anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives…
anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives…
[HTML][HTML] Epigenetic modifications in colorectal cancer: molecular insights and therapeutic challenges
AG Vaiopoulos, KC Athanasoula… - Biochimica et Biophysica …, 2014 - Elsevier
… correlation with disease clinicopathological features, suggesting … carcinogenesis from a
different point of view. Notably, CSCs … Natural compounds modulate epigenetic modifications in a …
different point of view. Notably, CSCs … Natural compounds modulate epigenetic modifications in a …
Modulating Epigenetic Modification Enzymes Through Relevant Epidrugs as a Timely Strategy in Anticancer Therapy
SA Ganai, SA Ganai - … Inhibitors in Combinatorial Anticancer Therapy, 2020 - Springer
… Another study through structure based virtual screening of one lakh drug like molecules …
Only recently through artificial intelligence based drug discovery, a novel and potent inhibitor of …
Only recently through artificial intelligence based drug discovery, a novel and potent inhibitor of …
Epigenetic modulation of antitumor immunity and immunotherapy response in breast cancer: biological mechanisms and clinical implications
J Yin, T Gu, N Chaudhry, NE Davidson… - Frontiers in …, 2024 - frontiersin.org
… correlates with aggressive clinicopathological features and … alone or in combination with
other anticancer drugs. In 2020, … will inform continued drug development efforts using these …
other anticancer drugs. In 2020, … will inform continued drug development efforts using these …
Epigenetic alterations in cancer and personalized cancer treatment
… to chemotherapy and targeted anticancer drugs. Moreover, … In particular, in the field of drug
development, the recognition … cancer epigenetics and of the future perspectives in cancer …
development, the recognition … cancer epigenetics and of the future perspectives in cancer …
[引用][C] Editorial (Hot Topic: Cross-Talking Metabolism and Epigenetics in Anti-Cancer Drug Design)
A Del Rio - Current Pharmaceutical Design, 2013 - ingentaconnect.com
… pathway proteins, discussing their clinicopathological relevance, structural data and drug
design perspectives [8]. Interestingly, … Modulation of epigenetic targets for anticancer therapy: …
design perspectives [8]. Interestingly, … Modulation of epigenetic targets for anticancer therapy: …