Molecular mechanisms of induction of persistent changes by estrogenic chemicals on female reproductive tracts and external genitalia

S Miyagawa, M Sato, T Iguchi - … of steroid biochemistry and molecular …, 2011 - Elsevier
induce malformations of the reproductive organs. In this review, we focus on the development
of female reproductive tracts and external genitalia, … estrogens and EDCs on these organs. …

[HTML][HTML] Endocrine disruptors acting on estrogen and androgen pathways cause reproductive disorders through multiple mechanisms: a review

S Amir, STA Shah, C Mamoulakis, AO Docea… - International Journal of …, 2021 - mdpi.com
chemicals (EDCs) is one of the major causes of reproductive … it is still able to induce the
estrogenic effects at very low … their exact interaction with molecular mechanisms involved in the …

Estrogen and female reproductive tract innervation: cellular and molecular mechanisms of autonomic neuroplasticity

MM Brauer, PG Smith - Autonomic Neuroscience, 2015 - Elsevier
… driven in part by estrogen-induced suppression of BMP4 synthesis… , the processes by which
chronic estrogen depletes vaginal … and external genitalia undergo significant remodeling; the …

Epigenetic effects of endocrine-disrupting chemicals on female reproduction: an ovarian perspective

AM Zama, M Uzumcu - Frontiers in neuroendocrinology, 2010 - Elsevier
… to EDC exposures in female reproductive system, with a special … months in DES-induced
uterine carcinomas Repression of … changes are effected by several molecular mechanisms now …

From malformations to molecular mechanisms in the male: three decades of research on endocrine disrupters

JA McLachlan, RR Newbold, ME Burow, SF Li - Apmis, 2001 - Wiley Online Library
… that estrogen can induce long-term functional changes. More … if genital tract development
was altered by estrogen at the … the development of the external genitalia of the mouse involves …

Estrogenic environmental chemicals and drugs: mechanisms for effects on the developing male urogenital system

JA Taylor, CA Richter, RL Ruhlen… - … biochemistry and molecular …, 2011 - Elsevier
estrogen during development results in permanent effects on … receptor levels induced by
elevated estrogen exposure, can … reproductive system and change postnatal growth rate and …

Human exposure to endocrine disrupting chemicals: effects on the male and female reproductive systems

S Sifakis, VP Androutsopoulos, AM Tsatsakis… - Environmental …, 2017 - Elsevier
… The molecular mechanism of action of EDCs with regard to the disorders of the … with the
estrogen receptor (ER). Environmental pollutants, such as TCDD can induce the expression of …

Genomic and nongenomic effects of estrogens: molecular mechanisms of action and clinical implications for male reproduction

M Luconi, G Forti, E Baldi - … Journal of steroid biochemistry and molecular …, 2002 - Elsevier
… to masculinization of external genitalia in the female, while in … during fetal life induces
reproductive disorders and genitalia … in detergents, paints and pesticides, seem to exert negative …

[HTML][HTML] Endocrine disruptors and endometrial cancer: molecular mechanisms of action and clinical implications, a systematic review

D Caserta, MP De Marco, AR Besharat… - … Journal of Molecular …, 2022 - mdpi.com
… limbs and oedema in the external genitalia must lead to a … and the high prevalence of
estrogen-dependent forms in this … of mycotoxin-induced estrogenicity, significantly suppressing …

[PDF][PDF] Influence of toxic chemicals on female reproduction: a review

JK Bhardwaj, P Saraf - Cell Biol Res Ther, 2014 - researchgate.net
induced ovarian follicular development in female SpragueDawley rat [69,148]. Mancozeb …
Some pesticides are estrogenic that leads to receptor mediated change in endocrinology of …