Mutational analysis of the HER2 gene in lung tumors from Caucasian patients: Mutations are mainly present in adenocarcinomas with bronchioloalveolar features

F Buttitta, F Barassi, G Fresu, L Felicioni… - … journal of cancer, 2006 - Wiley Online Library
… others in unselected lung adenocarcinomas.35, 39 … mutations in the tyrosine kinase domain
of the HER2 gene are relatively infrequent in lung adenocarcinomas from Caucasian patients

[HTML][HTML] CT features of HER2-mutant lung adenocarcinomas

P Sawan, AJ Plodkowski, AE Li, BT Li, A Drilon… - Clinical imaging, 2018 - Elsevier
… , its ground glass component, and the probability of harboring EGFR mutation [31]. In our
study, we found that HER2-mutant lung cancers occurred commonly in female …

Prognostic and predictive implications of HER2/ERBB2/neu gene mutations in lung cancers

K Tomizawa, K Suda, R Onozato, T Kosaka, H Endoh… - Lung cancer, 2011 - Elsevier
… to be present in a small fraction of lung adenocarcinomas. However … Mutational analysis and
immunohistochemistry … are significantly frequent in ADs with bronchioloalveolar carcinoma (…

HER2 gene mutations in non-small cell lung carcinomas: concurrence with Her2 gene amplification and Her2 protein expression and phosphorylation

M Suzuki, K Shiraishi, A Yoshida, Y Shimada, K Suzuki… - Lung Cancer, 2015 - Elsevier
… in ADC and SQC of Caucasian. Level 2 TCGA data of … Histological features of the
HER2-mutated adenocarcinomas. (A… noted lepidic features (formerly the bronchioloalveolar

Prevalence, Clinicopathologic Associations, and Molecular Spectrum of ERBB2 (HER2) Tyrosine Kinase Mutations in Lung Adenocarcinomas

ME Arcila, JE Chaft, K Nafa, S Roy-Chowdhuri… - Clinical cancer …, 2012 - AACR
… As a part of our standard panel of mutation analysis by mass … In this cohort of patients with
HER2-mutated lung cancers, … ADC with bronchioloalveolar carcinoma features (43). In our …

Epidermal growth factor receptor mutations in lung cancers

Y Yatabe, T Mitsudomi - Pathology international, 2007 - Wiley Online Library
features of adenocarcinomas harboring the mutations were reported to be frequent in those
with bronchioloalveolar features… % of non-Asian (mostly Caucasian) patients. When limited to …

Epidermal growth factor receptor mutation in lung cancer are linked to bronchioloalveolar differentiation

H Blons, JF Côté, D Le Corre, M Riquet… - The American journal …, 2006 - journals.lww.com
… , and adenocarcinoma (ADC) with bronchioloalveolar (BAC) … to mutational analysis. These
exons encompass all the EGFR … We then focused on tumors with ADC/BAC features and …

[HTML][HTML] … single institution-based retrospective study of surgically treated bronchioloalveolar adenocarcinoma of the lung: clinicopathologic analysis, molecular features …

C Casali, G Rossi, A Marchioni, G Sartori… - Journal of Thoracic …, 2010 - Elsevier
… BAC tumors in a population of Caucasian patients. We also … of lung cancer incidence
with adenocarcinomas greatly … K-RAS mutations in adenocarcinomas with significant impact …

[HTML][HTML] Salivary gland-type lung carcinomas: an EGFR immunohistochemical, molecular genetic, and mutational analysis study

RS Macarenco, TS Uphoff, HF Gilmer, RB Jenkins… - Modern Pathology, 2008 - Elsevier
… reported in adenocarcinomas of the lung. Neuroendocrine … features of patients with salivary
gland-type lung carcinomaanalysis of patients with non-small-cell lung carcinoma treated …

Lung adenocarcinoma: Sustained subtyping with immunohistochemistry and EGFR, HER2 and KRAS mutational status

V Sousa, C Rodrigues, M Silva, AM Alarcão… - Revista Portuguesa de …, 2015 - Elsevier
… , acinar, papillary, micropapillary, bronchioloalveolar (BA)/lepidic, or … Mutational analysis of
exon 19 deletion L858R point … 2 mutations and gender, we found that male lung cancer had …