NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity
G Stokman, L Kors, PJ Bakker, E Rampanelli… - Journal of Experimental …, 2017 - rupress.org
… decreased during acute renal ischemic injury and acute cellular rejection… NLRX1 function
extends to the control of mitochondrial activity and prevention of oxidative stress and apoptosis …
extends to the control of mitochondrial activity and prevention of oxidative stress and apoptosis …
NLRX1 alleviates lipopolysaccharide-induced apoptosis and inflammation in chondrocytes by suppressing the activation of NF-κB signaling
D Ma, Y Zhao, J She, Y Zhu, Y Zhao, L Liu… - International …, 2019 - Elsevier
… OA, we hypothesized that NLRX1 may participate in OA through regulating NF-κB signaling.
… apoptosis, associated with preventing oxidative stress and sustaining mitochondrial activity […
… apoptosis, associated with preventing oxidative stress and sustaining mitochondrial activity […
[HTML][HTML] NLRX1 knockdown attenuates pro-apoptotic signaling and cell death in pulmonary hyperoxic acute injury
HR Kim, MN Kim, EG Kim, JS Leem, SM Baek… - Scientific Reports, 2023 - nature.com
… in mitochondria 8,9 . Recent research has shown that NLRX1 has roles in modulation of
mitochondrial function, … NLRX1 deficiency dampens the inflammation and mortality induced by …
mitochondrial function, … NLRX1 deficiency dampens the inflammation and mortality induced by …
[HTML][HTML] NLRX1: versatile functions of a mitochondrial NLR protein that controls mitophagy
PY Bi, SA Killackey, L Schweizer, SE Girardin - Biomedical Journal, 2023 - Elsevier
… impact of NLRX1/UQCRC2 on mitochondrial function has not … and CNS, NLRX1 may dampen
inflammatory responses by … intrinsic apoptosis regulation occurs via NLRX1 interactions …
inflammatory responses by … intrinsic apoptosis regulation occurs via NLRX1 interactions …
[HTML][HTML] Focusing on the cell type specific regulatory actions of NLRX1
… injury and apoptosis by decreasing oxidative stress in a mouse … to the sites of infection or
tissue injury. Within the peripheral … NLRX1 dampens oxidative stress and apoptosis in tissue …
tissue injury. Within the peripheral … NLRX1 dampens oxidative stress and apoptosis in tissue …
[HTML][HTML] NLRX1 is a multifaceted and enigmatic regulator of immune system function
… NLRX1 actually shuttles from the cytosol to the mitochondria … oxidative stress is also a key
driver of cell death through JNK … NLRX1 reportedly exerts protective effects against apoptosis …
driver of cell death through JNK … NLRX1 reportedly exerts protective effects against apoptosis …
The regulatory role of NLRX1 in innate immunity and human disease
M Liu, K Liu, D Cheng, B Zheng, S Li, Z Mo - Cytokine, 2022 - Elsevier
… homeostasis and metabolic balance, as well as apoptosis and … The interaction between
oxidative stress and autophagy has … of NLRX1 in the regulation of mitochondrial function, and …
oxidative stress and autophagy has … of NLRX1 in the regulation of mitochondrial function, and …
NLRX1: a key regulator in mitochondrial respiration and colorectal cancer progression
Y Ding, W Sun, M Han, Z Liu, H Kang, X Ma, J Wang… - Medical Oncology, 2024 - Springer
… in response to tissue injury and apoptosis [13]. It is now widely accepted that … NLRX1
dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity. J Exp …
dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity. J Exp …
The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1
… The dependence of NLRX1 function on SARM1’s expression places NLRX1 as a protein …
to explain the function of NLRX1 and SARM1 in physiological and apoptotic conditions. Recent …
to explain the function of NLRX1 and SARM1 in physiological and apoptotic conditions. Recent …
[HTML][HTML] Mitochondria, oxidative stress and innate immunity
… with mtDNA oxidative damage trigger cell apoptosis by inducing … present in tissue injury.
For example, NLR family member X1 … During ischemia-reperfusion injury, NLRX1 is capable to …
For example, NLR family member X1 … During ischemia-reperfusion injury, NLRX1 is capable to …