… In this study, Ad5-based vaccine vectors were developed to direct the Pfs25-… targeting
Pfs25 were generated that induce antibodies in mice that significantly inhibit transmission of P. …

… of transmission-blocking (TB) vaccines (TBVs) targeting the … an AAV-based vaccine with
an adenovirus-based vaccine in a … viral vector for PfCSP and Pfs25 as a booster vaccine …

… Such vaccines elicit antibodies that inhibit parasites during … to Plasmodium falciparum
transmission-blocking vaccine … that multiple antibodies could target Pfs25 simultaneously. We …

… , Plasmodium falciparum, while in the mosquito vector, so the … of antibody recognition of
leading transmission-blocking … New adenovirus-based vaccine vectors targeting Pfs25 elicit …

… Vaccination via repeated bites with Plasmodium falciparum … to further improve the efficacy
of malaria targeted vaccines. … based immunizations were just as effective at eliciting anti-Pfs25 …

… class of gametocyte antigens, which may have the potential to elicit TB antibodies. The lack
… the TBA of antibodies against Pfs25 (42). Polyclonal antibodies targeting the male gamete …

… a multistage malaria vaccine (targeting both PfCSP and the … Pf(s25-CSP), an adenovirus-based
vaccine that has previously … -lasting antibody induction with a high level of anti-Pfs25 IgG …

… ) expressing either Plasmodium falciparum circumsporozoite … In addition, we generated a
multi-stage vaccine targeting … of AdHu5-AAV1 Pfs25 elicited durable anti-Pfs25 Ab with a high …

… The Plasmodium falciparum Pfs25 protein (Pfs25) is a … of Pfs25 in complex with antibodies
elicited by immunization via … Antibody targeting of Pfs25 can result in a significant reduction in …

… this study, the transmission reducing activity of the antibodies … responses over human elicited
to the same vaccine, we … dynamics of humoral immunity targeting the Pfs25-IMX313 domain …