[HTML][HTML] Non-lesional cerebellar damage in patients with clinically isolated syndrome: DTI measures predict early conversion into clinically definite multiple sclerosis

AV Kugler, M Deppe - NeuroImage: Clinical, 2018 - Elsevier
… also not permit to predict a “stable CIS course”, ie no conversion into MS over a … patients (N
= 16) that actually converted into MS during our study according to their individual conversion

What do we currently know about the clinically isolated syndrome suggestive of multiple sclerosis? An update

T Grzegorski, J Losy - Reviews in the Neurosciences, 2020 - degruyter.com
… also include isolated brainstem syndromes, cerebellar involvement, … Prediction based on
machine learning techniques is very … of conversion to MS is to estimate the risk of the disease

[HTML][HTML] DTI measurements in multiple sclerosis: evaluation of brain damage and clinical implications

E Sbardella, F Tona, N Petsas, P Pantano - Multiple sclerosis …, 2013 - hindawi.com
… CIS patients when they were studied again after conversion to … clinically isolated syndromes
suggestive of multiple sclerosis,” … , “Non-lesional white matter changes in pediatric multiple

[HTML][HTML] Cerebellar and/or brainstem lesions indicate poor prognosis in multiple sclerosis: a systematic review

Y Yang, M Wang, L Xu, M Zhong, Y Wang… - Frontiers in …, 2022 - frontiersin.org
… and the progression of clinically isolated syndromes (CIS) to … CIS has a higher risk of early
conversion to MS (HR, 2.0; 95% … have no statistical significance for predicting prognosis (18, …

[HTML][HTML] Evaluating magnetic resonance diffusion properties together with brain volumetry may predict progression to multiple sclerosis

J Stulík, M Keřkovský, M Kuhn, M Svobodová… - Academic …, 2022 - Elsevier
DTI parameters together with brain volumetry in patients with early-stage CIS may be useful
in predicting conversionClinically isolated syndrome (CIS) is a monophasic clinical episode …

[HTML][HTML] MRI prognostic factors in multiple sclerosis, neuromyelitis optica spectrum disorder, and myelin oligodendrocyte antibody disease

R Cortese, A Giorgio, G Severa… - Frontiers in Neurology, 2021 - frontiersin.org
… In patients with the clinically isolated syndrome (CIS), a higher number … non-lesional tissue
and along specific WM tracts (71, 72). These techniques include diffusion tensor imaging (DTI

[HTML][HTML] Default mode network structural integrity and cerebellar connectivity predict information processing speed deficit in multiple sclerosis

G Savini, M Pardini, G Castellazzi… - Frontiers in cellular …, 2019 - frontiersin.org
… exclusion: from the JHU ICBM-DTI-81 atlas, provided with FSL in … not to separate tissue in
lesional and non lesional masks. … the clinical translation potential of network measures for the …

MRI biomarkers of disease progression and conversion to secondary-progressive multiple sclerosis

E Tavazzi, R Zivadinov, MG Dwyer… - Expert Review of …, 2020 - Taylor & Francis
… , both within focal lesions and in the non-lesional tissue of both … with a so-called
clinically isolated syndrome, and is a … in this regard than traditional DTI-based measures [Citation113]. …

Grey matter pathology in clinically early multiple sclerosis: evidence from magnetic resonance imaging

D Chard, D Miller - Journal of the neurological sciences, 2009 - Elsevier
… of the disease burden borne by the brain; non-lesional WM is also … Limited work has
employed DTI or T1 relaxation time … of diffusion measures in clinically isolated syndromes and …

[HTML][HTML] MRI biomarkers of disease progression in multiple sclerosis: old dog, new tricks?

Y Barnett, JY Garber, MH Barnett - Quantitative Imaging in …, 2020 - ncbi.nlm.nih.gov
… MS/CIS patients with conversion to disability progression compared to … in a cohort of patients
with clinically isolated syndrome (CIS) and MS. … metrics, such change in lesion DTI or MTR. …