… distribution of adenovector through the ear. In this study we demonstrate that delivery of
adenovector to … delivery. Ad5 vector transduction and expression of the gfp transgene occurred …

… to tissues. The interplay between diffusion and clearance is key to determining the distribution
in the inner ear of substances applied to the RWM. Substances cleared from the fluids at …

… delivered a novel adenovirus vector that targets delivery of genes to … After vector delivery to
one inner ear in this bilateral … The opening was sealed with a piece of tissue and the wound …

… [73•] examined the pharmacodynamic of adenovector distribution within the inner ear
tissues of the mouse and found a significant basal to apical gradient of distribution with round …

… Pharmacodynamics of adenovector distribution within the inner ear tissues of the mouse.
Hear Res., 2007, 227, 53-58. [113] Oestreicher, E.; Arnold, W.; Ehrenberger, K.; Felix, D. …

… The tissue was incubated overnight at 4C in a humid … bcl-2 in the mouse inner ear by
immunohistochemical staining for … We chose adenovector as a delivery vehicle for this series of …

… potential of different tissues to act as adenovector targets, we … receptor distribution per se
explains adenovector targeting in … , mouse, rat, pig and dog can be infected with adenovectors …

… Most use is empiric and no good pharmacology studies have … adenovector, Kawamoto
demonstrated the delivery of math1 … Delivery of a viral vector into the mouse inner ear. Injection of …

… delivery to the VGLUT3 KO mouse inner ear through the round window membrane (RWM).
The post-auricular RWM injection method is minimally invasive with excellent hearing … tissues…

… transfer to the inner ear is the means and route of delivery. Vector … Adenovirus vector containing
the GDNF gene (Ad-GDNF) … through an intact round window membrane in mouse. Hum …