Pharmacokinetics and bioavailability comparison of generic and branded citalopram 20 mg tablets: an open-label, randomized-sequence, two-period crossover study …

T Jiang, Z Rong, Y Xu, B Chen, Y Xie, C Chen… - Clinical drug …, 2013 - Springer
study was to compare the pharmacokinetic characteristics of a new and a branded citalopram
20 mg formulation to support the marketing authorization of the test formulation in China. …

Comparison of bioavailability and bioequivalence of generic and brand name formulations of escitalopram oxalate tablets in healthy chinese population under fasting …

Q Li, H Huo, W Hu, Y Sui, Y Tang - Drug Design, Development and …, 2020 - Taylor & Francis
… Citation3 Escitalopram is a single S-enantiomer of citalopram… on a 12-month open-label
study of 486 patients treated with … of CYP2C19 poor metabolizers (PMs) within the Chinese

Impact of cytochrome P450 2C19 polymorphisms on citalopram/escitalopram exposure: a systematic review and meta-analysis

M Chang, G Tybring, ML Dahl, JD Lindh - Clinical pharmacokinetics, 2014 - Springer
… , the impact of CYP2C19 polymorphisms on citalopram or … citalopram 40 mg or escitalopram
20 mg being administered [3, 4]. Both citalopram and escitalopram are primarily metabolized

Pharmacogenetic perspectives in improving pharmacokinetic profiles for efficient bioequivalence trials with highly variable drugs: A review

PJ Huang, Y Hsieh, YW Huang, L Ding… - … of Pharmacokinetics, 2021 - Future Science
… [39] had conducted a conventional bioequivalence study in 24 healthy CYP2C19branded
citalopram 20 mg tablets: an open-label, randomized-sequence, two-period crossover study

Comparative bioavailability and pharmacokinetics of sirolimus tablets in healthy Chinese volunteers.

M Huang, J Chen, X Hu, J Liu, G Wu… - … journal of clinical …, 2013 - europepmc.org
… male volunteers and evaluate whether a generic tablet of … healthy Chinese volunteers was
eligible for this 6 mg single dose, randomized-sequence, open-label, 2-period crossover study

Pharmacokinetics of CYP2C9, CYP2C19, and CYP2D6 substrates in healthy Chinese and European subjects

S Lu, RA Nand, JS Yang, G Chen, AS Gross - European journal of clinical …, 2018 - Springer
pharmacokinetic determinants, including extent of absorption, body … metabolized by
CYP2C9, CYP2C19, or CYP2D6, and … were > 1, ranging from 1.04 (citalopram) to 2.94 (omeprazole), …

Pharmacokinetic and bioequivalence assessment of two formulations of tianeptine sodium in healthy male volunteers.

R Zheng, BH Kim - International journal of clinical pharmacology …, 2014 - europepmc.org
… the generic (test) formulation containing tianeptine sodium 12.5 mg and the branded (…
A randomized, two-sequence, two-treatment crossover study was conducted in healthy male …

[PDF][PDF] Prescribing Generic or Branded Antidepressants: What to Choose

J Sultana, F Parrino, G Trifiro - Ann Depress Anxiety, 2014 - researchgate.net
bioequivalence between generic and brand-name drugs is established by comparing their
bioavailability. … the packaging or pill colour/shape is different to that of the branded drug [18]. …

Establishment and Validation of a Transdermal Drug Delivery System for the Anti-Depressant Drug Citalopram Hydrobromide

Y Sun, Y Ni, R Wang, Z Qin, Z Liu, L Xiao, Y Liu - Molecules, 2024 - mdpi.com
study, the pharmacokinetics of the transdermal CTH delivery system were analyzed in rabbits.
The results showed that the system had good absorptiondosage range (20 mg to 40 mg) […

Allelic variation in 5-HTTLPR and the effects of citalopram on the emotional neural network

Y Ma, B Li, C Wang, W Zhang, Y Rao… - The British Journal of …, 2015 - cambridge.org
… of 30 mg citalopram, which is within the dose range (20–60mg) … Pharmacokinetic and plasma
hormone concentration studies have … bioavailability comparison of generic and branded