Phase II study of glucosamine with chondroitin on aromatase inhibitor-associated joint symptoms in women with breast cancer

H Greenlee, KD Crew, T Shao, G Kranwinkel… - … Care in Cancer, 2013 - Springer
… In summary, this phase II trial demonstrated that glucosamine and chondroitin … severe
aromatase inhibitor-induced joint pain. The study agents were well tolerated with minimal toxicities. …

Aromatase inhibitorassociated musculoskeletal pain: An overview of pathophysiology and treatment modalities

N Grigorian, SJ Baumrucker - SAGE Open Medicine, 2022 - journals.sagepub.com
… -receptor positive breast cancer in postmenopausal women. The … with vitamins and
glucosamine/chondroitin has been … of adverse musculoskeletal symptoms such as joint pain, …

[HTML][HTML] Musculoskeletal adverse events associated with adjuvant aromatase inhibitors

QJ Khan, AP O'Dea, P Sharma - Journal of Oncology, 2010 - hindawi.com
… for joint symptoms were examined in patients with breast cancer … of any controlled trials of
glucosamine specifically for the … Young et al., “Aromatase inhibitor-associated arthralgia and/…

Aromatase inhibitor-associated arthralgia syndrome

HJ Burstein - The Breast, 2007 - Elsevier
… endocrine treatment in postmenopausal women with early-stage breast cancer. Clinical
trials … While N-acetyl-glucosamine with or without chondroitin sulfate is used to promote joint

Aromatase inhibitor induced musculoskeletal syndrome: a significant problem with limited treatment options

JM Lombard, N Zdenkowski, K Wells… - … Care in Cancer, 2016 - Springer
… In the prevention setting, the IBIS II study reported musculoskeletal … -arm studies suggest
possible benefit from glucosamine … Rastelli et al. conducted a phase 2 study that showed high …

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast cancer

KE Roberts, IT Adsett, K Rickett… - Cochrane Database …, 2022 - cochranelibrary.com
… the end of the intervention; 2 studies, 183 women). The two studies, investigating vitamin D
and … AI cause side effects including joint and muscle pains and stiffness (aromatase inhibitors …

[HTML][HTML] Aromatase inhibitor-associated bone and musculoskeletal effects: new evidence defining etiology and strategies for management

S Gaillard, V Stearns - Breast Cancer Research, 2011 - Springer
… This study reports that women with joint symptoms at the … with vitamins, glucosamine and
chondroitin, omega fish oils, … -arm, open-label phase II study and improved functional status [101…

Symptoms: aromatase inhibitor induced arthralgias

DL Hershman, C Loprinzi, BP Schneider - … Outcomes for Breast Cancer …, 2015 - Springer
… -randomized phase II trial of glucosamine and chondroitin to … label phase 2 study of duloxetine
was studied in women with … on aromatase inhibitor-associated arthralgias in women with …

[HTML][HTML] Aromatase inhibitor-associated musculoskeletal syndrome: understanding mechanisms and management

T Hyder, CC Marino, S Ahmad… - Frontiers in …, 2021 - frontiersin.org
… all breast cancer (53%), including invasive HR+ breast cancer … In a phase II trial, ninety
women on adjuvant anastrozole were … The discrepancy between the two studies may partially be …

Aromatase inhibitor-induced arthralgia in early breast cancer: what do we know and how can we find out more?

OS Din, D Dodwell, RJ Wakefield… - Breast cancer research …, 2010 - Springer
two study groups [51]. Again, this instrument did not take into account arthralgia and other
joint symptoms. … , testosterone, blue citrus, glucosamine and chondroitin. The results of these …