Prevalence of integrase strand transfer inhibitor resistance mutations in antiretroviral-naive HIV-1-infected individuals in Cameroon

BM Wenk, HA Mbunkah, NN Nsanwe… - Journal of …, 2021 - academic.oup.com
… Since pretreatment HIV-1 drug resistance can jeopardize the success of ART, and … -1
subtypes in Cameroon, we investigated the prevalence of pretreatment HIV-1 resistance to INSTIs. …

HIV-1 integrase diversity and resistance-associated mutations and polymorphisms among integrase strand transfer inhibitor-naive HIV-1 patients from Cameroon

SG Mikasi, JO Gichana, C Van der Walt… - AIDS research and …, 2020 - liebertpub.com
… This is the first study to investigate the prevalence of … In antiretroviral-naive patients, L74M
occurs in 0.5% to 10% … We suggest that IN sequencing of all HIV-1-infected patients before …

[HTML][HTML] Prevalence of HIV-1 Natural Polymorphisms and Integrase-Resistance-Associated Mutations in African Children

DB Fofana, H Diarra, I Guindo, MK Savadogo… - Viruses, 2023 - mdpi.com
strand transfer, that is, the binding of the INI to the integraseprevalence was defined as the
percentage of HIV-1-infected … These mutations were observed in Cameroon and Ethiopia [24,…

[HTML][HTML] Low level of HIV-1C integrase strand transfer inhibitor resistance mutations among recently diagnosed ART-naive Ethiopians

M Kiros, DA Tefera, H Andualem, A Geteneh… - Scientific Reports, 2023 - nature.com
… options available to newly HIV-1 infected patients, and it is … Accordingly, this study found out
that the prevalence of … is higher than detection rate in studies from Cameroon 8.1–10% 22,25 …

Primary resistance against integrase strand transfer inhibitors in integrase strand transfer inhibitor-naive patients failing first-and second-line ART in Tanzania

S Henerico, E Lyimo, AN Makubi… - Journal of …, 2022 - academic.oup.com
… the prevalence of INSTI primary resistance mutations in Tanzanian patients exposed to ART
… dolutegravir in treatment-naive patients was conducted in Cameroon, wherein major INSTI …

Limited emergence of resistance to integrase strand transfer inhibitors (INSTIs) in ART-experienced participants failing dolutegravir-based antiretroviral therapy: A …

A Abdullahi, IM Kida, UA Maina… - Journal of …, 2023 - academic.oup.com
… WGS of plasma samples collected from 61 HIV-1-infected … This study found a low prevalence
of resistance to … of the NRTI mutation K65R, along with low-level resistance to tenofovir …

[HTML][HTML] Rate of virological failure and HIV-1 drug resistance among HIV-infected adolescents in routine follow-up on health facilities in Cameroon

CI Penda, M Moukoko Mbonjo, J Fokam, ABD Djeuda… - PLoS …, 2022 - journals.plos.org
… with a high prevalence of drug resistance mutations (DRM), … the newly recommended
integrase strand transfer inhibitors (… Clinical and virologic follow-up in perinatally HIV-1-infected

Investigating the structural impact of hiv-1 integrase natural occurring polymorphisms and novel mutations identified among group m subtypes circulating in sub …

SG Mikasi - 2020 - scholar.sun.ac.za
… INSTI naïve patients from South Africa (SA) and Cameroon (CR), … , Cameroon is the country
with the highest prevalence rates … Integrase strand transfer inhibitors (INSTIs) can be used as …

Drug resistance mutations of HIV type 1 non-B viruses to integrase inhibitors in treatment-naive patients from sub-saharan countries and discordant interpretations

M Monleau, AF Aghokeng, BA Nkano… - AIDS research and …, 2012 - liebertpub.com
… -naive HIV-1-infected patients that were collected between 2006 and 2008 in Cameroon (n=30), …
HIV-1 integrase sequence variability in antiretroviral naive patients and in triple-class …

[HTML][HTML] Factors associated with HIV-1 resistance to integrase strand transfer inhibitors in Spain: Implications for dolutegravir-containing regimens

, … for the Study of Antiretroviral Drug Resistance - Frontiers in …, 2022 - frontiersin.org
… (INSTI)-containing regimens in HIV-1-infected patients have … in the frequency of INSTI-resistant
viruses between patients … INSTI resistance mutation found among these patients was …