… We assessed whether the calcium antagonist diltiazem (0.50 mg/kg bolus … prevent the
profibrillatory effect or even partially restore the antifibrillatory effect of a class I antiarrhythmic drug, …

… enhance the prolongation of conduction time by 60% and do not prevent the 30% … manifested
profibrillatory properties (more pronounced than those of other class I antiarrhythmic drugs)…

… influence of other drugs, such as calcium channel blockers [10]… Effects of ischemia alone in
18 anesthetized, openchest pigs … antiarrhythmic action could then change into a profibrillatory …

… of this study was to compare in anesthetized, open-chest pigs, … in situ. Naunyn-Schmiedeberg's
Arch Pharmacol … of action of calcium antagonists in myocardial ischemia. Am J Cardiol …

… related to myocardial ischemia in the in situ heart of anesthetized open-chest pigs subjected
… widely used in the latest decades to prevent ventricular fibrillation (VF) in acute myocardial …

… It was desirable that, in this study, myocardial ischaemia was not only … direction the
profibrillatory effect of antiarrhythmic drugs such as … Study in the porcine in situ heart. Cardiovasc …

… of IVA on the threshold of ischemic VF in a pig model of brief … the profibrillatory or antifibrillatory
effects of a variety of drugs including … β-blockers and calcium antagonists increase VFT by …

… in infarct size in intact in situ hearts. Thus the major goal of the … ischaemia and reperfusion
in isolated perfused guinea pig … profibrillatory effects, particularly in patients with a previous …

… , calcium channel antagonists prevent the profibrillatory effect or … The model used in this
study is a pig model of brief left … in preventing calcium overload during myocardial ischemia and …

… myocardial ischemia and class Ic antiarrhythmic drugs is now … class Ic drugs exhibit
profibrillatory effects in the presence of … and other antiarrhythmic drugs in preventing lethal …