Protective effects of nebivolol and reversal of endothelial dysfunction in diabetes associated with hypertension

A Georgescu, D Popov, E Dragan, E Dragomir… - European journal of …, 2007 - Elsevier
… as in hypertension. This study aims to decipher the potential action of nebivolol in the potential
… and/or regression of the renal artery endothelial dysfunction in diabetes associated with …

Nebivolol: impact on cardiac and endothelial function and clinical utility

JE Toblli, F DiGennaro, JF Giani… - Vascular Health and …, 2012 - Taylor & Francis
… complicated hypertension, such as that associated with diabetes … The effects of these agents
on endothelial dysfunction may … injury, nebivolol has been shown to have protective effects. …

Different effects of antihypertensive drugs on endothelial dysfunction

P Puddu, GM Puddu, E Cravero, A Muscari - Acta cardiologica, 2004 - Taylor & Francis
… and nebivolol, seem to be provided with specific endothelium… structural and endothelial
vascular protective effect. In … essential hypertension, in which endothelial dysfunction plays a key …

Nebivolol exerts beneficial effects on endothelial function, early endothelial progenitor cells, myocardial neovascularization, and left ventricular dysfunction early after …

SA Sorrentino, C Doerries, C Manes, T Speer… - Journal of the American …, 2011 - jacc.org
… , and observed that nebivolol therapy exerts additional effects on LV dysfunction early after
… findings suggest that the effects of nebivolol treatment on LV dysfunction early after MI were …

Antihypertensive drugs and reversing of endothelial dysfunction in hypertension

S Taddei, A Virdis, L Ghiadoni, I Sudano… - Current hypertension …, 2000 - Springer
… Essential hypertension is associated with impaired endo… ), impairing its beneficial and
protective effects on the vessel wall. … a restoration of the nebivolol vasodilating effect, which was …

Effects of antihypertensive drugs on endothelial dysfunction: clinical implications

S Taddei, A Virdis, L Ghiadoni, I Sudano, A Salvetti - Drugs, 2002 - Springer
hypertension is associated with endothelial dysfunction, … protective effects on the vessel
wall. In prospective studies, … whether new compounds such as nebivolol, which activates the L-…

Loss of arterial and renal nitric oxide bioavailability in hypertensive rats with diabetes: effect of β-blockers

R Preston Mason, R Kubant, RF Jacob… - … of hypertension, 2009 - academic.oup.com
Nebivolol reversed these effects in a manner consistent with … the hypothesis that nebivolol
can restore endothelial NO … to compare the effects of these agents on endothelial function and …

Nebivolol reverses endothelial dysfunction in essential hypertension: a randomized, double-blind, crossover study

N Tzemos, PO Lim, TM MacDonald - Circulation, 2001 - Am Heart Assoc
nebivolol can reverse endothelial dysfunction, we conducted a double-blind, crossover trial
comparing the effects of nebivolol and … NO bioactivity in patients with essential hypertension. …

Effects of nebivolol versus other antihypertensive drugs on the endothelial dysfunction in patients with essential hypertension

B Li, Q Zhang, H Zhang, C Wang, R Xiu - Bioscience Reports, 2020 - portlandpress.com
… that nebivolol did not have a better endothelium-protective effectNebivolol is not a unique
endothelial function-protective agent … Reversal of endothelial dysfunction is a key point in the …

Nebivolol dilates human penile arteries and reverses erectile dysfunction in diabetic rats through enhancement of nitric oxide signaling

J Angulo, HM Wright, P Cuevas… - The journal of sexual …, 2010 - academic.oup.com
Nebivolol has also been shown to relax mouse cavernosal tissue and to improve endothelial
function in … in endothelial cells from diabetic rats with hypertension after treatment with …