Cxcl10+ monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation

A Giladi, LK Wagner, H Li, D Dörr, C Medaglia… - Nature …, 2020 - nature.com
… symptoms, and is characterized by short-term specific depletion of Saa3 + and Cxcl10 +
monocyte subsets as we have shown in two independent experiments. These results highlight …

Publisher Correction: Cxcl10+ monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation

A Giladi, LK Wagner, H Li, D Dörr… - Nature …, 2020 - pubmed.ncbi.nlm.nih.gov
Publisher Correction: Cxcl10+ monocytes define a pathogenic subset in the central nervous
system during autoimmune neuroinflammation Publisher Correction: Cxcl10 + monocytes …

[HTML][HTML] CXCL10 Is Associated with Increased Cerebrospinal Fluid Immune Cell Infiltration and Disease Duration in Multiple Sclerosis

SN Blandford, NJ Fudge, CS Moore - Biomolecules, 2023 - mdpi.com
… between CXCL10 and various immune cell subsets in the … chemoattraction of macrophages,
monocytes, and activated T … as being dysregulated in CNS inflammation and MS, a …

IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation

A Amorim, D De Feo, E Friebel, F Ingelfinger… - Nature …, 2022 - nature.com
… and recruitment Cxcl10 + monocytes during inflammation. … pathogenic phagocyte
subsets during neuroinflammation. … and data matrix correction. To find the common clusters …

[HTML][HTML] Cytokine and immune cell profiling in the cerebrospinal fluid of patients with neuro-inflammatory diseases

G Lepennetier, Z Hracsko, M Unger… - … of neuroinflammation, 2019 - Springer
… with immune cell subsets and standard CSF parameters. … Further attempts aimed to distinguish
between different pathogens … show a negative correlation with CSF monocytes [20], which …

[HTML][HTML] IFN-β acts on monocytes to ameliorate CNS autoimmunity by inhibiting proinflammatory cross-talk between monocytes and Th cells

J Rasouli, G Casella, LLW Ishikawa, R Thome… - Frontiers in …, 2021 - frontiersin.org
… Mice were kept in specific pathogen–free conditions in 12/12 h … To identify a subset of
monocytes that expresses type-I IFNs, … -β suppresses CNS inflammation by acting on monocytes to …

[HTML][HTML] Unique primed status of microglia under the systemic autoimmune condition of lupus-prone mice

A Nomura, D Noto, G Murayama, A Chiba… - Arthritis Research & …, 2019 - Springer
… in the absence of apparent inflammation in the central nervous system (CNS), … Cxcl10 were
concurrent with increased numbers of T cells and monocytes, especially Ly6C lo monocytes

Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation

MJC Jordão, R Sankowski, SM Brendecke, Sagar… - Science, 2019 - science.org
… to be able to express high levels of CXCL10, CCL5, and CD74, … hi monocytes rapidly die
during autoimmune inflammation, the … contributes to the pathogenesis of neuroinflammation, we …

[HTML][HTML] Utility of CSF cytokine/chemokines as markers of active intrathecal inflammation: comparison of demyelinating, anti-NMDAR and enteroviral encephalitis

K Kothur, L Wienholt, SS Mohammad, EM Tantsis… - PLoS …, 2016 - journals.plos.org
monocyte and neutrophil recruitment to the inflammation site, … However a subset of cytokines
showed positive correlations … and CXCL10) were also identified as markers of inflammation

[HTML][HTML] CD8+ T cells in the central nervous system of mice with herpes simplex infection are highly activated and express high levels of CCR5 and CXCR3

L Lind, A Svensson, K Thörn, M Krzyzowska… - Journal of …, 2021 - Springer
… Mice were kept under pathogen-free conditions at the Department of Rheumatology and …
expression of CXCL10. CXCL10 is also upregulated in other neuroinflammatory infections like …