… at the mammalian neuromuscular synapse. We demonstrated that rab3a(−) mouse diaphragm
synapses have a diminished pool of docked and membrane-adjacent vesicles, although …

… that Rab3a maintains the pool of fusion competent vesicles … We found that in Rab3a(−)
synapses the decrease in quantal … of Rab3a deletion on Ca 2+ sensitivity of transmitter release is …

… presynaptic transmitter release through regulation of vesicle trafficking and membrane fusion.
… muscle preparations from diaphragm as well as soleus muscles from Rab3A KO mice, we …

… mouse diaphragm synapse synapsin and Rab3a have opposite effects on some properties
of quantal release and synaptic … gene deletion reduced vesicle docking similar to the Rab3a …

… that rab3A has a function upstream of vesicle fusion in the … 6) and a decrease in the amount
of synaptic vesicles at 200-1000-… that rab3A deletion affects the transport of synaptic vesicles …

… , a fusion pore opens allowing NT release into the synaptic cleft… types in the mouse diaphragm
are visibly distinguishable, and … as Synapsin I deletion only affects type I synapses, while …

… Rab3a deletion reduces vesicle docking and transmitter release at the mouse diaphragm
synapse. … Evidence for recycling of synaptic vesicle membrane during transmitter release at the …

… (but see [47]; Rab3A deletion reduced vesicle docking at the … of the mouse stomach, and
deletion of Slp2-a reduces both … , a greatly reduced number of synaptic vesicles docked to the …

… Synaptic transmission is initiated by synaptic vesicle (SV) … , could reduce the stress on the
hemifusion diaphragm and … in neurotransmitter release in rab3A-deficient synapses: Either …

… 40% decrease in both docked and undocked synaptic vesicles in wild-type nerve terminals
of the mouse diaphragm. … II gene deleted animals, but surprisingly it did not decrease vesicle …