… copy number loss of FHIT is associated with lymph node metastasis (LNM) and suggest that
the down-regulation of Fhit indicates poor prognosis in early oral squamous cell carcinoma (…

… (LNM) in early oral squamous cell carcinoma (OSCC). … (10 losses) associated with cervical
LNM (P < 0.05). Among them, loss of 3p14.2 for the FHIT gene was the most frequent one (5 …

… : Abnormalities of FHIT, a candidate tumor suppressor gene, … a Fhit-negative tumor experienced
locoregional recurrence … lymph nodes, and the presence of extracapsular spread (ECS). …

… for cervical lymph node metastasis and extracapsular spread … patients at risk for recurrence
or metastatic disease can be … amplification and loss of expression of P16 gene, because both …

… Squamous cell carcinoma represents the most frequent … correlate with tumor differentiation
or lymph node metastasis. … , indicating a minor impact of HPV associated carcinogenesis in …

… no correlation between the frequent genomic loss of Caspase 8 … suffer from lymph node
metastasis (LNM) or recurrence. … we have demonstrated frequent gain of multiple genes at 20q…

… neck squamous cell carcinoma may be the consequence of loss of … (HNSCC) is one of the
10 most frequent tumors in the world. … tumor resection margins or lymph node extra capsular …

… from leukoplakia to oral squamous cell carcinoma (OSCC) … recurrent chromosomal alterations
in lymph node metastasis-… lymph node metastasis in OSCC, along with loss of 3p14.2 (…

… Loss of FHIT expression in POLs that progressed to … Stage, lymph node metastasis, tumor
size, relapse at the … that FHIT down-regulation is an early frequent event in oral carcinogenesis …

… features, including tumor stage, development of metastasis and tobacco … frequent losses of
the ERBB4 gene (2q33.3-q34) only in … located within this region, such as FHIT, may also be …