… In the case of c-myc RNA degradation in vitro, cleavage within an AU-rich region has been
… within the c-fos AU-rich region during mRNA degradation (data not shown). Rapid poly(A) …

… ARE-containing mRNAs are triggered for rapid degradation (5, … element to facilitate rapid
deadenylation of 3-globin mRNA, the … complete removal of the "dangerous" c-fos mRNA from …

… Poly(A) tail removal is a critical first step in the decay pathway for … as the first step in mRNA
degradation, but by different kinetics. For … The two distinct ways for facilitating deadenylation …

… : accelerated poly(A) shortening leads to subsequent decay of … and to better address the
generality of the c-fos ARE-directed … sequence to facilitate complete removal of the 3' poly(A) tail …

… step in degradation of this mRNA (53) and that the c-fos ARE … bothpromoting poly(A) removal
and destabilizing the mRNA (… , facilitating analysis of changes in poly(A) tail length during …

… Removal of one uridine residue from either end of the nonamer (… of labile mammalian mRNAs
besides c-fos mRNA, prompting … facilitate further studies of the mechanisms by which these …

… end of a GM-CSF AU-rich sequence hinders the efficiency of the ARE following changes
in cellular … Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3! …

… Both the c-fos AUrich element and the coding region instability determinant appear to function
by facilitating rapid removal of the c-fos poly(A) tail as a first step in the mRNA degradation …

… mRNA is targeted for rapid degradation, we have examined the importance of poly(A) tail
removal for c-/os mRNA … of the c-/os AU-rich element into the 3' untranslated region of p-globin …

… c-fos AU-rich element specifies its mRNA-destabilizing function. … (A) tail of BFB mRNA and
its deletion derivatives. The … cellular RNAs as indicated by degraded rRNAs (Figure 4D). This …