Spinal cord transcriptional profile analysis reveals protein trafficking and RNA processing as prominent processes regulated by tactile allodynia

DE Coyle - Neuroscience, 2007 - Elsevier
… pain independent of the genes regulated by nerve injury. … the spinal cord that are uniquely
regulated by tactile allodynia in rats. Using subtractive methods, genes regulated by allodynia

Comparative transcriptome profiling of the human and mouse dorsal root ganglia: an RNA-seq–based resource for pain and sensory neuroscience research

P Ray, A Torck, L Quigley, A Wangzhou, M Neiman… - Pain, 2018 - journals.lww.com
… Our analyses reveal an hDRG-enriched protein-coding gene … nerve transcriptomes suggests
trafficking of neuronal mRNA to … and spinal cord with respect to the rest of the CNS. A third …

RNA-seq of spinal cord from nerve-injured rats after spinal cord stimulation

KE Stephens, Z Chen, E Sivanesan, SN Raja… - Molecular …, 2018 - journals.sagepub.com
… repetitive spinal cord stimulation represses transcription of … To identify genes that were
differentially regulated following … Principal component analysis shows segregation of the …

… in Acute and Chronic Allodynia: Using Human Psychophysics, Sensory Analysis, Glial Modulation and Functional Proteomics in the Dorsal Horn of the Spinal Cord

S Shaikh - 2017 - search.proquest.com
tactile and cold allodynia arise when normal sensory traffic is … proteomic profiling, analyse
regulation of protein expression … ALE meta-analysis reveals dissociable networks for affective …

Identification of IncRNA expression profile in the spinal cord of mice following spinal nerve ligation-induced neuropathic pain

BC Jiang, WX Sun, LN He, DL Cao, ZJ Zhang… - Molecular …, 2015 - journals.sagepub.com
… , characterized by mechanical allodynia and heat hyperalgesia. … regulate gene expression
via interfering with transcription, … to regulate gene expression [37] and traffic cellular protein

[HTML][HTML] Transcriptome profiling of long noncoding RNAs and mRNAs in spinal cord of a rat model of paclitaxel-induced peripheral neuropathy identifies potential …

Y Li, C Yin, B Liu, H Nie, J Wang, D Zeng… - Journal of …, 2021 - Springer
… and get involved in transcriptional modulation or regulating … The mechanical allodynia lasted
till the end of our … Astrocytes and microglia in spinal cord dorsal (SCDH) horn play important

RNA profiling of human dorsal root ganglia reveals sex differences in mechanisms promoting neuropathic pain

PR Ray, S Shiers, JP Caruso, D Tavares-Ferreira… - Brain, 2023 - academic.oup.com
… Our analysis reveals clear sex differences in sets of genes … spontaneous pain, hyperalgesia
or allodynia in a region at or … through this important transcriptional regulatory pathway. For …

[HTML][HTML] Spared nerve injury causes sexually dimorphic mechanical allodynia and differential gene expression in spinal cords and dorsal root ganglia in rats

FHG Ahlström, K Mätlik, H Viisanen, KJ Blomqvist… - Molecular …, 2021 - Springer
… to be important in the induction of allodynia in female rats. … in females imply a divergent
change in transcription in DRG … Pathway and biological process analysis revealed, in particular, …

Analyses of long non-coding RNA and mRNA profiles in the spinal cord of rats using RNA sequencing during the progression of neuropathic pain in an SNI model

J Zhou, Y Fan, H Chen - RNA biology, 2017 - Taylor & Francis
… Both mechanical allodynia and thermal sensitivity were … lncRNAs regulate gene expression
and traffic cellular protein complexes, … Our analyses revealed complex network relationships …

Dorsal root ganglion transcriptome analysis following peripheral nerve injury in mice

S Wu, B Marie Lutz, X Miao, L Liang, K Mo… - Molecular …, 2016 - journals.sagepub.com
… L4 spinal nerve ligation produced mechanical allodynia in … play a key role in regulating the
transmission of peripheral … of kappa opioid receptors in spinal cord and DRG to vary with the …