… by human immunodeficiency virus type 1 (HIV-1) strains are … strain SF162, selected for
replication in the C8166 T-cell line. … , the loss of macrophage-tropism by one variant was due to a …

… -1 SF162 adaptation for replication in the C8166 T cell line … a non-functional vpu impairs
macrophage tropism. Thus, in … Biological phenotype of human immunodeficiency virus type 1 …

… SF162 (8), inserted into the backbone of the molecular T-cell-… observed previously in HeLa
cells and in the CD4 T-cell line … 5A), suggesting a better adaptation of the primary isolate than …

… We used SF162 vpu in all chimeric viruses in this study because its amino acid sequence is
… YU-2, a highly macrophage-tropic strain cloned directly from brain tissue of an AIDS patient, …

… of HXBc2, a T cell line-adapted HIV-1 isolate, drastically reduce the ability of the mutant …
can affect the T-cell line and macrophage tropism of human immunodeficiency virus type …

… neutralized T-cell line adapted strain of HIV-1. This data indicates that macrophage-tropism
in … The Human Immunodeficiency Virus (HIV) is an enveloped virus with glycoprotein spikes …

… not cosegregate with either macrophage or T-cell line tropism. However, … another
laboratory-adapted, HBCE cell-tropic strain, NL4-3 (1), and … b Macrophage tropism was …

… 1 SF162 isolate (9) selected by viral propagation on CXCR4-expressing T-cell lines acquired
… , and D-10 each have one additional unique mutation that impacts replication capacity and …

… , rev, and vpu (23). NF-Xho contains almost exclusively the NL4-3 … by 1 aa and the SF162
strain differs by three residues from … T-cell or macrophage tropism, cytopathogenicity, and CD4 …

… T-cell-line-adapted strains of human immunodeficiency virus … We included MN, IIIB, and
SF162.LS in this analysis to allow … envelope genes from human immunodeficiency virus type 1 …