… stroke (29,30). The aim of this study was to determine the potential efficacy of linagliptin against
stroke in diabetic and normal mice … diabetic and obese patient receiving DPP-4 inhibitor …

… show that DPP-4 inhibitors counteract stroke in the normal and diabetic mouse brain [10], …
In our preliminary experiment, we compared the effect of transient global cerebral ischemia (…

… DPP-4 inhibitors with linear pharmacokinetics, linagliptin is … compared to patients with identified
diabetes prior the stroke (68… linagliptin versus glimepiride in patients with type 2 diabetes …

… We demonstrated that the DPP-4 inhibitor linagliptin … and improved neurological deficit
compared with control mice. … diabetes complicated with stroke [26, 27], suggesting that …

… of linagliptin against stroke in diabetic and normal mice by using a drug administration
paradigm and a dose that mimics a type 2 diabetic and obese patient receiving DPP-4 inhibitor …

… suggesting neuroprotective effects of DPP-4 inhibitors in acute stroke, it is still … linagliptin
prior to stroke increases the number of surviving neurons more than glimepiride in diabetic mice…

… -fed mice was treated with either linagliptin or glimepiride for … t test was used for the comparison
between the standard diet … Importantly, we demonstrated that Lina or Gli can counteract …

… linagliptin, administered after stroke in the diabetic mouse, could counteract cognitive
impairment and brain … study comparing linagliptin with glimepiride in T2D patients suggested that …

… cell infiltration in MCA strokes (9), but this putative mechanism of DPP-4 inhibition was not
… type 2 diabetic patients will be randomized to receive linagliptin compared with glimepiride, …

… that linagliptin reduces acute brain damage after stroke [23], in this work we studied whether
the DPP-4 inhibitor linagliptin had … the difference in the regulation of these factors by DPP-4 …