… We developed and characterized a competitive ELISA for the … used to measure the active
form of ADAMTS-4 in a bovine … ADAMTS-4 in the present study was from an ex vivo model. …

… : We established and characterized a competitive ELISAs for measuring the active forms
of ADAMTS-4 and MMP-9 specifically. Specificity of the antibodies was tested by ELISAs and …

… of ADAMTS-4 and ADAMTS-5 to bovine cartilage degradation … a bovine full-depth cartilage
ex vivo model stimulated with … Competitive ELISAs were developed for estimation of active …

… -5 versus ADAMTS-4 in human OA cartilage explants [12]. … was assessed in bovine cartilage
and OA human cartilage explants. … ADAMTS-5 in cartilage ex vivo models to characterize its …

… and ADAMTS-4 were generated and in vitro, ex vivo and in vivo … ADAMTS-5 inhibition over
ADAMTS-4, as measured by ARGS … Here, we demonstrate characterization and validation of …

… complementarity determining region COMP cartilage oligomeric … Active ADAMTS-4 levels
are also increased in SF from these … In ex vivo cartilage explants systems, the initial enzymes …

… cartilage metabolism, several in vitro and ex vivo model … /TNFα stimulated bovine cartilage
explants, the active enzymes … aggrecanase 2, also designated ADAMTS-4 15 and ADAMTS-5 …

… Bovine cartilage explants were cultured with oncostatin M (… effects on the cartilage ECM,
by measuring the translational … turnover is characterized by cartilage tissue deterioration. This …

… The absorbance was measured at 558 nm on an ELISA … These measurements show that it
is possible to measure … has been published for bovine cartilage explants. Another possibility is …

… affecting articular cartilage and is characterized by disrupted cartilage … ex vivo. Enhanced
expression of p55 may contribute to OA … (B) ADAMTS-4 and GAPDH blots were measured by …