… peroxisome proliferator-activated receptors ligands are associated with the inhibition of angiotensin converting enzyme expression in streptozotocin-induced diabetic …
H Toba, S Miki, T Shimizu, A Yoshimura, R Inoue… - European journal of …, 2006 - Elsevier
… In conclusion, we demonstrated here the direct antioxidative and anti-inflammatory effects of
… the streptozotocin-induced diabetic rat model. Such vasoprotective effects of PPARs ligands …
… the streptozotocin-induced diabetic rat model. Such vasoprotective effects of PPARs ligands …
Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II–infused rats: role of peroxisome proliferator–activated receptor-γ
QN Diep, M El Mabrouk, JS Cohn, D Endemann… - Circulation, 2002 - Am Heart Assoc
… as a mechanism linking diabetes mellitus and hypertension. … -affinity ligands for peroxisome
proliferator–activated receptor (… ACE inhibition or antagonism of AT 1 receptors prevented or …
proliferator–activated receptor (… ACE inhibition or antagonism of AT 1 receptors prevented or …
Activation of peroxisome proliferator-activated receptor-β/-δ (PPARβ/δ) prevents endothelial dysfunction in type 1 diabetic rats
AM Quintela, R Jimenez, M Gomez-Guzman… - Free Radical Biology …, 2012 - Elsevier
… expressed PPARβ/δ also exhibits anti-inflammatory … Coincubation with the PPARβ/δ ligand
GW0742 had no effect on the … of cyclic GMP in aorta from streptozotocin-induced diabetic rats …
GW0742 had no effect on the … of cyclic GMP in aorta from streptozotocin-induced diabetic rats …
Antihypertensive effects of peroxisome proliferator-activated receptor-β/δ activation
… atherosclerotic, anti-inflammatory and vasodilatory effects (47… /δ ligands, which produced a
strong inhibitory effect on aortic … include the upregulation of antioxidant genes, such as GPx1, …
strong inhibitory effect on aortic … include the upregulation of antioxidant genes, such as GPx1, …
Inhibition of vascular angiotensin-converting enzyme by telmisartan via the peroxisome proliferator–activated receptor γ agonistic property in rats
S Takai, D Jin, M Kimura, K Kirimura, H Sakonjo… - Hypertension …, 2007 - nature.com
… PPARγ ligands inhibit NADPH oxidase expression in the streptozotocin-induced diabetic rat
aorta in … Ulker S, McMaster D, McKeown PP, Bayraktutan U: Impaired activities of antioxidant …
aorta in … Ulker S, McMaster D, McKeown PP, Bayraktutan U: Impaired activities of antioxidant …
Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator–activated receptor-γ agonist in hypercholesterolemia
L Tao, HR Liu, E Gao, ZP Teng, BL Lopez… - Circulation, 2003 - Am Heart Assoc
… reported to exert anti-inflammatory effects and attenuate … function in diabetic animal models
and diabetic patients. However, … may inhibit superoxide-producing enzyme(s) expression and/…
and diabetic patients. However, … may inhibit superoxide-producing enzyme(s) expression and/…
Molecular mechanisms and therapeutic perspectives of peroxisome proliferator‐activated receptor α agonists in cardiovascular health and disease
… the ligand-activated transcription factor of a nuclear receptor … cell-tube in streptozotocin-induced
diabetic mice are absent by … -remodeling, anti-inflammatory, and antioxidative effects on …
diabetic mice are absent by … -remodeling, anti-inflammatory, and antioxidative effects on …
Cardiac peroxisome-proliferator-activated receptor expression in hypertension co-existing with diabetes
TI Lee, YH Kao, YC Chen, NH Pan, YK Lin… - Clinical …, 2011 - portlandpress.com
… effects of PPAR ligands on cardiac PPAR isoform expression … have demonstrated the
anti-inflammatory effect of PPAR agonists … enzyme expression in streptozotocin-induced diabetic …
anti-inflammatory effect of PPAR agonists … enzyme expression in streptozotocin-induced diabetic …
A combination of PPAR-γ agonists and HMG CoA reductase inhibitors (statins) as a new therapy for the conservative treatment of AAS (aortic aneurysm syndromes)
GP Sorice, F Folli - Medical hypotheses, 2009 - Elsevier
… in diabetic fatty rats, and as shown in diabetic rats, the direct anti-oxidant and anti-inflammatory
effects of PPAR-γ ligands … effects are associated with the inhibition of the expression of …
effects of PPAR-γ ligands … effects are associated with the inhibition of the expression of …
Targeting endothelial dysfunction and inflammation
… 4 inhibitors, peroxisome proliferator-activated receptor δ … vascular beneficial, anti-oxidative
and anti-inflammatory in either … RAS inhibitors, PPARδ ligands, GLP-1 elevators and GLP-1 …
and anti-inflammatory in either … RAS inhibitors, PPARδ ligands, GLP-1 elevators and GLP-1 …