The effect of actin disrupting agents on contact guidance of human embryonic stem cells

S Gerecht, CJ Bettinger, Z Zhang, JT Borenstein… - Biomaterials, 2007 - Elsevier
contact guidance responses of hESCs in the presence of actin disrupting agents (ADAs). …
, we examined the effect of contact guidance of hESCs on cell cytoskeleton organization and …

Phenomenon of “contact guidance “on the surface with nano-micro-groove-like pattern and cell physiological effects

F Zhou, L Yuan, H Huang, H Chen - Chinese Science Bulletin, 2009 - Springer
… of actin disrupting agents attenuated the “contact guidance”, if human embryo stem cells
were … the findings, they deemed that the actin played a crucial role in the occurrence of “contact

Contact guidance of smooth muscle cells is associated with tension-mediated adhesion maturation

AC Saito, TS Matsui, T Ohishi, M Sato… - Experimental Cell …, 2014 - Elsevier
… The inset on the left panel represents a corresponding image of F-actin and nuclei. Scale …
and size of zyxin were decreased in human mesenchymal stem cells on the grating, but other …

Expression of Oct4 in human embryonic stem cells is dependent on nanotopographical configuration

YP Kong, CH Tu, PJ Donovan, AF Yee - Acta biomaterialia, 2013 - Elsevier
… to nucleate the polymerization of actin stress fibers. Additionally, disrupting dorsal stress fiber
… -produced nanotopography to address the hypothesis of whether human embryonic stem

[HTML][HTML] Cellular and subcellular contact guidance on microfabricated substrates

C Leclech, C Villard - Frontiers in Bioengineering and Biotechnology, 2020 - frontiersin.org
… on stem cells and topography-induced stem cell differentiation, this … Disturbing the link
between FAs and actin stress fibers while … elements involved in contact guidance, such as actin. It …

On the role of RhoA/ROCK signaling in contact guidance of bone-forming cells on anisotropic Ti6Al4V surfaces

A Calzado-Martín, A Méndez-Vilas, M Multigner… - Acta biomaterialia, 2011 - Elsevier
stem cells on submicrometric grooves, but not of osteoblasts. These findings show that
RhoA/ROCK signaling is involved in contact guidance of bone-related cells on … revealed that actin

Contact guidance of mesenchymal stem cells by flagellin-modified substrates: Aspects of cell-surface interaction from the point of view of liquid crystal theory

K Hileuskaya, B Kakasi, V Kulikouskaya… - Colloids and Surfaces A …, 2023 - Elsevier
… with organization of the actin cytoskeleton, size and shape of … human embryonic stem
cell-derived mesodermal progenitor … engineering methods without disturbing the polymerizing …

Nanotopographical control for maintaining undifferentiated human embryonic stem cell colonies in feeder free conditions

D Bae, SH Moon, BG Park, SJ Park, T Jung, JS Kim… - Biomaterials, 2014 - Elsevier
… In the absence of nanotopographical cues, the cytoskeleton was reorganized into actin stress
fibers disrupted E-cadherin mediated cellcell adhesions, and its anchorage to mature FAs …

Engineering substrate topography at the micro‐and nanoscale to control cell function

CJ Bettinger, R Langer… - Angewandte Chemie …, 2009 - Wiley Online Library
Contact guidance is a leading example of a naturally occurring phenomenon that is … h
embryonic stem cellsActin polymerization dynamics involved in cytoskeleton rearrangement are …

[HTML][HTML] Anisotropic forces from spatially constrained focal adhesions mediate contact guidance directed cell migration

A Ray, O Lee, Z Win, RM Edwards, PW Alford… - Nature …, 2017 - nature.com
cells, aligned architectures providing contact guidance cues induce constrained focal
adhesion maturation and associated F-actin … would disrupt the contact guidance response. This …