… of exogenous surfactant administration in this … surfactant therapy for patients with established
ALI/ARDS have been variable.[6] [9] As a result, the future of exogenous surfactant therapy, …

… will find a place in our armamentarium of treatment of ALI/ARDS in the future. … of surfactant
therapy in several randomized clinical trials in adults with ALI/ARDS may relate at least in part …

… Of note, gas exchange as reflected by PaO2 values during the first three days of treatment, …
surfactants are undergoing clinical evaluation for the treatment of patients with ALI/ARDS. …

… 1 The AECC definitions of ALI/ARDS are widely used clinically, although they have …
Expanded definitions of ALI/ARDS have also been developed using the Delphi technique. 8 …

… for the design of future surfactant replacement clinical trials … on surfactant to stabilise alveolar
air sacs during respiration. … of the ALI/ARDS population according to the surfactant synthetic …

… , concluded that the incidence of ALI/ARDS in the USA was … While we know that ALI/ARDS
occurs less often in children … that exogenous surfactant therapy shows greater efficacy while in …

… Novel therapies in development for treatment of ALI/ARDS … consider exogenous surfactant
administration as a therapeutic … Ongoing and future research efforts will provide important …

… suffice, hence our attempt at a targeted functional approach. … New techniques of surfactant
administration in combination … reported in the use of surfactant in ALI/ARDS, we agree with …

… , while overall surfactant performance follows a reduction in the functional large surfactant
aggregates and damage to surfactant … at repair in the lung; both offer potential targets for future …

… pharmacologic therapies, such as corticosteroids, surfactant, … new and investigational
therapies for ALI/ARDS that are the … protocol that will be used for future trials (Table 2). This more …