The mechanism of TGF-β/miR-155/c-Ski regulates endothelialmesenchymal transition in human coronary artery endothelial cells

J Wang, W He, X Xu, L Guo, Y Zhang, S Han… - Bioscience …, 2017 - portlandpress.com
Human coronary artery endothelial cells (HCAECs) have the potential to undergo fibrogenic
endothelialmesenchymal transition … to the pathogenesis of cardiac fibrosis. Recently, the …

Apigenin attenuates TGF-β1-stimulated cardiac fibroblast differentiation and extracellular matrix production by targeting miR-155-5p/c-Ski/Smad pathway

F Wang, K Fan, Y Zhao, ML Xie - Journal of Ethnopharmacology, 2021 - Elsevier
… Recent studies have revealed that miR-155 can negatively regulate the c-Ski expression
in cultured human coronary artery endothelial cells (Wang et al., 2017c). In the present study, …

[HTML][HTML] miR‑155‑5p downregulation inhibits epithelial‑to‑mesenchymal transition by targeting SIRT1 in human nasal epithelial cells

N Yang, H Cheng, Q Mo… - Molecular Medicine …, 2020 - spandidos-publications.com
… (EMT) in nasal epithelial cells is involved with tissue … molecular mechanisms through which
miR‑155‑5p regulated EMT … processes, such as coronary heart disease (23), atherosclerosis (…

Epigenetic regulation of endothelial-to-mesenchymal transition in chronic heart disease: histone modifications, DNA methylation, and noncoding RNAs

MS Hulshoff, X Xu, G Krenning… - … thrombosis, and vascular …, 2018 - Am Heart Assoc
human coronary endothelial cellscardiac endothelial cells. This suggests that these miRNAs
are upregulated as a protective mechanism or that these miRNAs are differently regulated

MicroRNA targets and biomarker validation for diabetes-associated cardiac fibrosis

ZQ Jin - Pharmacological Research, 2021 - Elsevier
Endothelial cells can also be converted to cardiac fibroblasts through endothelial-mesenchymal
transition … TGF-β1 treatment of human coronary artery endothelial cells increased …

… inhibitor-1 promotes cardiac fibrosis in aged mice: involvement of constitutive transforming growth factor-β signaling and endothelial-to-mesenchymal transition

AK Ghosh, WS Bradham, LA Gleaves, B De Taeye… - Circulation, 2010 - Am Heart Assoc
… pERK1/2-positive cells were detected in the cardiac vascular walls in … endothelial cells
appear to be more susceptible to the phenomenon called endothelial-mesenchymal transition in …

c-Ski, Smurf2, and Arkadia as regulators of TGF-β signaling: new targets for managing myofibroblast function and cardiac fibrosis

RH Cunnington, M Nazari… - Canadian journal of …, 2009 - cdnsciencepub.com
… , regulates them in a ‘close to the gene’ or specific mode, as opposed to that of I-Smad7. …
In a model for kidney fibrosis using a human proximal tubular epithelial cell line (HKC-8), …

Over-expression of c-SKI inhibits isoprenaline-induced myocardial fibrosis in mice

Y ZHANG, Y XIANG, Y ZHANG… - Basic & Clinical …, 2021 - journal11.magtechjournal.com
cardiac fibrosisꎻ endothelial-mesenchymal transition (End-MT)ꎻ transcription factor 心肌纤维
化(cardiac … peptide protects against cardiac fibrosis in diabetic mice heart by regulating

[HTML][HTML] MicroRNA profiles of human peripheral arteries and abdominal aorta in normal conditions: MicroRNAs-27a-5p,-139-5p and-155-5p emerge and in atheroma …

S Collura, C Ciavarella, C Morsiani, I Motta… - Mechanisms of Ageing …, 2021 - Elsevier
… miR-profiling differences in human femoral, abdominal aortic, and carotid arteries aiming
at the identification of miRs likely involved in epigenetics changes of these arteries in normal …

Update on pediatric lung transplantation: mir-ando into the mechanisms of chronic lung allograft dysfunction in children

C Conrad - Current Opinion in Organ Transplantation, 2020 - journals.lww.com
mechanisms in children are differently regulated than that of … of the TGF-β pathway, a
pathway integral to the formation of … down regulated and their target genes (B-cell development) …