Thermally-prepared polymorphic forms of cilostazol
GW Stowell, RJ Behme, SM Denton, I Pfeiffer… - Journal of …, 2002 - Elsevier
… In the case of cilostazol, an antithrombotic agent, the only crystalline form reported … cilostazol
and potentially improve its bioavailability, an investigation into potential polymorphic forms …
and potentially improve its bioavailability, an investigation into potential polymorphic forms …
[HTML][HTML] Comparative study of different crystallization methods in the case of cilostazol crystal habit optimization
T Tari, P Szabó-Révész, Z Aigner - Crystals, 2019 - mdpi.com
… cilostazol is limited owing to its poor aqueous solubility and oral bioavailability. Our aim was
to produce cilostazol … size distribution and stable polymorphic form to increase its dissolution …
to produce cilostazol … size distribution and stable polymorphic form to increase its dissolution …
Physical and dissolution characterization of cilostazol solid dispersions prepared by hot melt granulation (HMG) and thermal adhesion granulation (TAG) methods
YC Chen, HO Ho, JD Chiou, MT Sheu - International journal of …, 2014 - Elsevier
… powder, thus the crystalline form of a compound is always less soluble than the corresponding
amorphous form (Ansel et al., 1999). Furthermore, when the ratio of cilostazol:TPGS was …
amorphous form (Ansel et al., 1999). Furthermore, when the ratio of cilostazol:TPGS was …
[PDF][PDF] Hydrophilic sugars for enhancing dissolution rate of cilostazol: effect of wet co-processing
… cooling of cilostazol is believed to result in polymorphic transition… It may possibly reflect
polymorphic transition of the drug in … Polymorphism has been reported for cilostazol upon thermal …
polymorphic transition of the drug in … Polymorphism has been reported for cilostazol upon thermal …
The investigation of MCM-48-type and MCM-41-type mesoporous silica as oral solid dispersion carriers for water insoluble cilostazol
Y Wang, L Sun, T Jiang, J Zhang, C Zhang… - Drug development …, 2014 - Taylor & Francis
… for the stable crystalline form of CLT is 159 CCitation40, while the amorphous form had no
… was evidence that there might be a crystalline transition during the drug loading procedure. …
… was evidence that there might be a crystalline transition during the drug loading procedure. …
Can crystal engineering be as beneficial as micronisation and overcome its pitfalls?: A case study with cilostazol
KS Gouthami, D Kumar, R Thipparaboina… - International journal of …, 2015 - Elsevier
… of cilostazol by crystal engineering, using habit modification method and compare with
micronized cilostazol … polymorphic forms, of which form A is the most stable form. The other two …
micronized cilostazol … polymorphic forms, of which form A is the most stable form. The other two …
Preparation and optimization of glyceryl behenate-based highly porous pellets containing cilostazol
… reported cases of cilostazol polymorphism after melting and coolingCitation 40 , the sintering
temperature used in this study was not high enough to alter its crystalline form. The FTIR …
temperature used in this study was not high enough to alter its crystalline form. The FTIR …
[HTML][HTML] An oral formulation of cilostazol nanoparticles enhances intestinal drug absorption in rats
C Yoshioka, Y Ito, N Nagai - Experimental and …, 2018 - spandidos-publications.com
… Therefore, we are now investigating the effect of each of the CLZ polymorphic forms (Form
AC) in the CLZ/Rnano tablet on stability in re-dispersion, drug absorption, and treatment of …
AC) in the CLZ/Rnano tablet on stability in re-dispersion, drug absorption, and treatment of …
[HTML][HTML] Cilostazol-loaded poly (ε-Caprolactone) electrospun drug delivery system for cardiovascular applications
… B, which may spontaneously convert overtime back to form A … incorporation of the hydrophobic
drug - cilostazol (CIL) into the … Our study demonstrates no change in CIL polymorphic form …
drug - cilostazol (CIL) into the … Our study demonstrates no change in CIL polymorphic form …
A systematic approach to design and prepare solid dispersions of poorly water-soluble drug
S Verma, VS Rudraraju - AAPS PharmSciTech, 2014 - Springer
… For this investigation, cilostazol (CIL) was selected as model drug, which was classified as a
… 6 and 7) all proved that the sample of CIL received was crystalline and polymorphic form A (…
… 6 and 7) all proved that the sample of CIL received was crystalline and polymorphic form A (…