… be a safe and effective drug for the treatment of human hormone-refractory breast cancer. …
against human tumors implanted in nude mice sc as xenografts of hormone-refractory MDA-MB…

… , as well as tumors arising in genetically modified mice do … (sc) implantation of a glass cylinder
in mice results in the formation … removal in the PD tumors: cytostasis and apoptosis. These …

… weight were observed in mice treated with YM155 during the … After orthotopic implantation
of PC-3, control mice showed a … defects and apoptosis in various human cancer cells including …

… In all experiments, mice bearing transplanted tumors were … -treated tumors resulted in
an increase in apoptosis or a … with hormone-refractory metastatic breast cancer treated with …

… Mice were treated as from Day 6 after tumor implant when a … and apoptosis induction or tumor
weight in untreated and treated … human tumor xenografts implanted in immunosuppressed …

… transplanted. For example, the CWR22 xenograft tumor grows in nude mice and recurs
as hormone-refractory … Blockage of apoptosis may be an important feature of hormone-refractory …

… of hormone-refractory human prostate cancer implanted … imaging of tumour growth in
nude mice. Mechanistically, in … human xenografts of lymphomas and breast cancers in nude …

… in apoptosis induction in hormone refractory prostate cancer … implantation in the mammary
gland of female nude mice, all … grade invasive and metastatic human tumors, it is suggested …

… (SCID)-human prostate cancer and breast cancer model of … surface of the previously
implanted bone (38, 39). The … the tumor volumes in each group on the day when all mice were …

… cancer agent in vivo, the growth of LNCaP cells as heterotopically implanted tumors in nude
mice … with the progression of prostate cancer to its hormone refractory state. To test this …