The Ewing family of tumors (Ewing's sarcoma and primitive neuroectodermal tumor [PNET])
is the second most common malignant bone tumor (after osteogenic sarcoma) in children …

Although rare, cancer is the leading cause of death from disease in children less than 15
years of age in the United States. 143 With the consistent use of effective multimodality …

Background The late effects of bone marrow transplantation, including cancer, need to be
determined in a large population at risk. Methods We studied 19,229 patients who received …

Context.—There is a substantial risk of a second cancer for persons with hereditary
retinoblastoma, which is enhanced by radiotherapy. Objective.—To examine long-term risk …

Objective: The purpose of the study is to investigate chemoreduction and adjuvant treatment
(AT) for retinoblastoma and its effect on complete retinal tumor control, vitreous seed control …

Medulloblastoma, one of the most common central nervous system (CNS) tumors in
children, requires aggressive multimodality therapy including surgery, radiation therapy, and …

Background Radiotherapy and chemotherapy are associated with an increased risk of
second malignant neoplasm (SMN). An association between SMN and familial aggregation …

Epidemiologic evidence on the relation between occupational and environmental radiation
and cancer is reviewed. Studies of pioneering radiation workers, underground miners, and …

OSTEOSARCOMA IS the most common primary bone malignancy affecting children and
young adults. Their outlook, compared with the results of treatment available 25 years ago …

BACKGROUND Second malignant neoplasms have been noted infrequently in survivors of
osteosarcoma treated before 1970. METHODS For the above reason, the authors surveyed …