Abstract Learning Objectives After completing this course, the reader will be able to: Discuss
etiologic and biologic factors in osteosarcoma. Select the appropriate diagnostic work-up for …

PURPOSE: To compare treatment plans from standard photon therapy to intensity
modulated X-rays (IMRT) and protons for craniospinal axis irradiation and posterior fossa …

Ionizing radiation and a variety of genetic conditions are thought to explain 5–10% of
childhood cancers. Infection with Epstein–Barr virus (EBV) in parts of Africa and human …

Background: Compared with the general population, carriers of germline mutations in RB1
who survive retinoblastoma (ie, hereditary retinoblastoma survivors) are at increased risk of …

Background: Survivors of childhood cancer are at risk for secondary breast cancer. Other
than previous chest radiation therapy, risk factors for secondary breast cancer have not been …

We evaluated the long-term results obtained in 402 patients with non-metastatic Ewing's
sarcoma (ES) of the bone treated in a single institution with adjuvant and neoadjuvant …

Cancer is a very rare disease in children. There have been impressive gains in survival in
recent years, and these have been achieved through the use of chemotherapy and national …

PURPOSE: To evaluate the causes of chemoreduction failure in retinoblastoma and to
analyze the associated factors for eventual treatment with external beam radiotherapy and …

Soft tissue sarcoma (STS) is one of the most frequent second primary cancer that occurs
during the first 20 years following treatment for a solid cancer in childhood. Our aim was to …

purpose. To characterize the pharmacology and toxicity of intravenous versus focal
carboplatin delivery in the rabbit eye. methods. Pharmacological distribution of carboplatin …