The rising incidence of second cancers: patterns of occurrence and identification of risk factors for children and adults.

LM Morton, K Onel, RE Curtis, EA Hungate… - American Society of …, 2014 - europepmc.org
As the population of cancer survivors has increased and continues to age, the occurrence of
second cancers has risen dramatically-from 9% of all cancer diagnoses in 1975-1979 to …

The cyclophosphamide equivalent dose as an approach for quantifying alkylating agent exposure: a report from the Childhood Cancer Survivor Study

DM Green, VG Nolan, PJ Goodman… - Pediatric blood & …, 2014 - Wiley Online Library
Background Estimation of the risk of adverse long‐term outcomes such as second malignant
neoplasms and infertility often requires reproducible quantification of exposures. The …

[HTML][HTML] Radiation-induced sarcomas of the head and neck

A Thiagarajan, NG Iyer - World journal of clinical oncology, 2014 - ncbi.nlm.nih.gov
With improved outcomes associated with radiotherapy, radiation-induced sarcomas (RIS)
are increasingly seen in long-term survivors of head and neck cancers, with an estimated …

Classification, imaging, biopsy and staging of osteosarcoma

ZS Kundu - Indian journal of orthopaedics, 2014 - Springer
Osteosarcoma is the most common primary osseous malignancy excluding malignant
neoplasms of marrow origin (myeloma, lymphoma and leukemia) and accounts for …

Second nonocular tumors among survivors of retinoblastoma treated with contemporary photon and proton radiotherapy

RV Sethi, HA Shih, BY Yeap, KW Mouw, R Petersen… - Cancer, 2014 - Wiley Online Library
BACKGROUND The leading cause of death among patients with hereditary retinoblastoma
is second malignancy. Despite its high rate of efficacy, radiotherapy (RT) is often avoided …

Risk of subsequent malignant neoplasms in long-term hereditary retinoblastoma survivors after chemotherapy and radiotherapy

JR Wong, LM Morton, MA Tucker… - Journal of Clinical …, 2014 - ascopubs.org
Purpose Hereditary retinoblastoma (Rb) survivors have increased risk of subsequent
malignant neoplasms (SMNs). Previous studies reported elevated radiotherapy (RT)-related …

[HTML][HTML] Current knowledge and future research directions in treatment-related second primary malignancies

LM Morton, AJ Swerdlow, M Schaapveld… - European Journal of …, 2014 - Elsevier
Abstract Currently, 17–19% of all new primary malignancies occur in survivors of cancer,
causing substantial morbidity and mortality. Research has shown that cancer treatments are …

Reducing radiation exposure in early-onset scoliosis surgery patients: novel use of ultrasonography to measure lengthening in magnetically-controlled growing rods

OM Stokes, EJ O'Donovan, D Samartzis, CH Bow… - The Spine Journal, 2014 - Elsevier
Background context Magnetically-controlled growing rod (MCGR) technology has been
reported for the treatment of early-onset scoliosis (EOS). Such technology allows for regular …

Risk of second bone sarcoma following childhood cancer: role of radiation therapy treatment

B Schwartz, MA Benadjaoud, E Cléro, N Haddy… - Radiation and …, 2014 - Springer
Bone sarcoma as a second malignancy is rare but highly fatal. The present knowledge
about radiation-absorbed organ dose–response is insufficient to predict the risks induced by …

Second malignant neoplasms and cardiovascular disease following radiotherapy

LB Travis, AK Ng, JM Allan, CH Pui, AR Kennedy… - Health …, 2014 - journals.lww.com
Second malignant neoplasms (SMNs) and cardiovascular disease (CVD) are among the
most serious and life-threatening late adverse effects experienced by the growing number of …