Childhood cancer: occurrence, treatment and risk of second primary malignancies

S Zahnreich, H Schmidberger - Cancers, 2021 - mdpi.com
Simple Summary Childhood cancers are mostly of unknown etiology and represent
devastating diagnoses. The clinical benefits of steadily increasing tumor control and survival …

Current status of management and outcome for patients with Ewing sarcoma

AC Hesla, A Papakonstantinou, P Tsagkozis - Cancers, 2021 - mdpi.com
Simple Summary Ewing sarcoma is a highly aggressive malignancy affecting primarily
children and adolescents. It is the second most common bone sarcoma among children …

[HTML][HTML] Incidence of radiation induced sarcoma attributable to radiotherapy in adults: A retrospective cohort study in the SEER cancer registries across 17 primary …

A Snow, A Ring, L Struycken, W Mack, M Koç… - Cancer …, 2021 - Elsevier
Background Previous studies have noted the incidence of radiation-induced sarcomas (RIS)
but have not investigated the relative risk (RR) of developing RIS based on primary tumor …

Subsequent malignant neoplasms in retinoblastoma survivors

AWM Fabius, M van Hoefen Wijsard, FE van Leeuwen… - Cancers, 2021 - mdpi.com
Simple Summary Currently survival from retinoblastoma exceeds 95% in high-
income/resource countries. Life expectancy within the heritable retinoblastoma population is …

[HTML][HTML] Identification of genetic predispositions related to ionizing radiation in primary human skin fibroblasts from survivors of childhood and second primary cancer …

M Marron, LK Brackmann, H Schwarz… - JMIR Research …, 2021 - researchprotocols.org
Background Therapy for a first primary neoplasm (FPN) in childhood with high doses of
ionizing radiation is an established risk factor for second primary neoplasms (SPN). An …

[HTML][HTML] A predictive model for chemotherapy-related diminished ovarian reserve in reproductive-age women

MM Hopeman, KE Cameron, M Prewitt, K Barnhart… - Fertility and sterility, 2021 - Elsevier
Objective To develop and internally validate a clinical predictive tool to assess the likelihood
that a young cancer patient will experience diminished ovarian reserve (DOR) after …

Antitumor effect of sclerostin against osteosarcoma

H Ideta, K Yoshida, M Okamoto, J Sasaki, M Kito… - Cancers, 2021 - mdpi.com
Simple Summary Osteosarcoma is highly variable and heterogeneous, which is one of the
reasons for its resistance to treatment. Because osteosarcoma is defined by abnormal bone …

Sarcomas of the sellar region: a systematic review

F Guerrero-Perez, N Vidal, M Lopez-Vazquez… - Pituitary, 2021 - Springer
Purpose and methods Sarcomas of the sellar region are uncommon and unexpected
tumors. Here, we review the cases reported in literature via a systematic search. Results …

The epidemiology and pathogenesis of sarcoma

W Kabir, PFM Choong - Sarcoma: A Practical Guide to Multidisciplinary …, 2021 - Springer
Sarcomas are a group of rare malignant neoplasms of mesenchymal origin which may occur
in skeletal and extraskeletal tissue, including muscles, tendons, fat, synovium, fibrous tissue …

Epidemiology of bone and soft tissue sarcomas

PJ Lupo, LG Spector, S O'Brien, JD Schiffman… - Sarcomas of Bone and …, 2021 - Springer
Bone and soft tissue sarcomas collectively make up 12% of all pediatric malignancies. While
there have been significant improvements in treatment for these sarcomas, mortality and …