Osteosarcoma is the most common primary malignant tumour of the bone. Osteosarcoma
incidence is bimodal, peaking at 18 and 60 years of age, and is slightly more common in …

Osteosarcoma represents a rare cause of cancer in the general population, accounting for<
1% of malignant neoplasms globally. Nonetheless, it represents the main cause of …

Radiation-induced breast sarcomas (RIBS) are rare entities representing< 1% of all primary
breast malignancies, limiting most reports to small retrospective case series. They constitute …

Background Total body irradiation (TBI) is an established part of conditioning regimens prior
to stem cell transplantation in childhood leukemia but is associated with long-term toxicity …

The most common primary malignant tumor of bone in children is osteosarcoma (OS).
Nowadays, the prognosis and the introduction of chemotherapy in OS have improved …

Simple Summary Ewing sarcoma (EwS) is a malignant bone and soft tissue cancer that
requires intensive treatment with multiple chemotherapies and either surgery, irradiation, or …

Background Eye‐preserving therapy in retinoblastoma comprises systemic chemotherapy,
but studies analyzing the efficacy of different chemotherapy regimens are scarce. Methods …

It is established that moderate-to-high doses of ionising radiation increase the risk of
subsequent cancer in the exposed individual, but the question arises as to the risk of cancer …

Background Brachytherapy (BT) delivers highly conformal radiation and spares surrounding
tissues, which may limit late effects in pediatric, adolescent, and young adult (AYA) patients …

The effects of radiation and chemotherapy on the musculoskeletal (MSK) system are
diverse, and interpretation may be challenging. The different lines of treatment have effects …